O6.6. lack of antipsychotic medication effects on white matter microstructure in schizophrenia

DiscussionWith state of the art data-processing methods we only found small areas of white matter integrity deficits in our predominantly medication-na ïve patients. This is consistent with prior reports of limited white matter alterations at disease onset that may progress with illness duration. Our data suggests that a short-term course of antipsychotic medication may not alter white matter microstructure, but studies with longer follow up durat ions will be important to determine long term effects of antipsychotic medications.
Source: Schizophrenia Bulletin - Category: Psychiatry Source Type: research