O4.6. genome-wide association study, heritability estimation and polygenic risk analysis of susceptibility to infections in 65,534 individuals with severe mental disorders and population controls

DiscussionOur findings will illuminate the genetic architecture of acquiring infections, and the genetic associations with mental disorders exploring the possible genetic component of the known association between infections and severe mental disorders, such as schizophrenia. Furthermore, we will for the first time in a large population based study explore the associations with HLA alleles to infections and severe mental disorders.
Source: Schizophrenia Bulletin - Category: Psychiatry Source Type: research