The Relationship Between Peak Cough Flow and Respiratory Function Testing (Spirometry), and the Factors That Influence This, Post Bilateral Sequential Single Lung Transplantation: A Cross-sectional Feasibility Study at a Single Centre Cardiothoracic Transplantation Unit

Spirometry is gold standard for detecting chronic lung allograft (CLAD) dysfunction. Peak cough flow (PCF) assesses cough strength and identifies those at risk of developing respiratory tract infections, which contribute to the development of CLAD. Normal adult PCF 440-1200 L/min, ≥ 270 L/min PCF demonstrates adequate cough, ≤ 160 L/min demonstrates inefficient cough. Study Aims: 1. To evaluate the feasibility of recruitment and PCF testing alongside standard care 2. To examine the relationship between PCF and forced vital capacity (FVC) and PCF and forced expiratory volu me in one second (FEV1), and the factors that influence this post bilateral sequential single lung transplant (BSSLTx).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research