Long-Term Changes in Pulmonary Haemodynamics after Continuous-Flow Left Ventricular Assist Device Implantation in Advanced Heart Failure Patients

Pulmonary hypertension (PH) due to left heart disease (LHD) is a marker of poor prognosis in patients with advanced heart failure.Fixed PH with elevated pulmonary vascular resistance (PVR) is a major contraindication to heart transplantation.Continuous-flow left ventricular assist devices (cf-LVADs) can reduce pulmonary pressures in patients with advanced heart failure with reduced ejection fraction (HFrEF).The purpose of the study was to assess long-term effect of cf-LVAD on type II PH in HFrEF,and to evaluate the association of clinical and haemodynamic variables with PH persistence after LVAD implantation.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research