Genital tuberculosis in postmenopausal women with variable clinical presentations: A report of 3 cases

Publication date: Available online 30 March 2018 Source:Case Reports in Women's Health Author(s): Ashima Arora, Shameema Anvar Sadath Genital tuberculosis is usually diagnosed in young women being assessed for infertility. After menopause it usually presents with symptoms resembling endometrial malignancy, such as postmenopausal bleeding, persistent vaginal discharge and pyometra. The diagnosis is made by detection of acid-fast bacilli on microscopy or bacteriological culture and/or presence of epithelioid granuloma on biopsy. Anti-tubercular therapy involves the use of rifampicin, isoniazid, pyrazinamide and ethambutol. Surgery is indicated if a pelvic mass and recurrence of pain or bleeding persist after 9 months of treatment. Three cases of genital tuberculosis in postmenopausal women with different clinical presentations are reported. The first woman presented with ascites and weight loss. The second had postmenopausal bleeding with a pipelle biopsy suggestive of endometrial intraepithelial neoplasia. The third presented with weight loss and a palpable abdominal mass. Pelvic malignancy was initially suspected but a diagnosis of tuberculosis was made following pre-operative endometrial biopsy, bacteriological culture and intra-operative frozen section. All three women responded to anti-tubercular therapy.
Source: Case Reports in Womens Health - Category: OBGYN Source Type: research

Related Links:

ConclusionsThe aim of this case report is to describe our surgical strategy to manage a giant vascular malformation of the tongue and improve quality of life through a median glossectomy with trapezoidal wedge resection of the tongue, as previously described for surgical management of macroglossia.
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - Category: ENT & OMF Source Type: research
We present a case of GCA in a patient who presented with jaw claudication and occlusal pain. A 78-year-old man visited our department with left-sided facial pain associated with mastication. He also reported spontaneous left-sided facial pain and diminished vision. Based on his age, his new-onset left-sided headache, and a high erythrocyte sedimentation rate, he was diagnosed with GCA with immediate initiation of prednisolone (PSL) therapy. His fever subsided the following day. A temporal artery biopsy (TAB) was performed 7 days after hospitalization and showed a false-negative result. His left-sided facial pain and headac...
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - Category: ENT & OMF Source Type: research
Abstract Background: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder with recurrent abdominal pain and altered defecation habits. We here attempted to determine the effect of acupuncture on IBS. Methods: Randomized controlled trials (RCTs) published in CNKI, VIP, Wanfang, PubMed, Cochrane Library, EMBASE, Web of science, and ClinicalTrials.gov till July 17, 2019 were searched. Outcomes were total efficacy rates, overall IBS symptom scores, or global quality of life scores. Standardized mean difference (SMD) with 95% confidence intervals (CI) and risk ratio (RR) with 95% CI were calcul...
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
Publication date: Available online 9 December 2019Source: Drug Discovery Today: Disease ModelsAuthor(s): Prashant Sharma, Elena-Raluca Nicoli, Jenny Serra-Vinardell, Marie Morimoto, Camilo Toro, May Christine V. Malicdan, Wendy J. IntroneSince the initial description of Chediak-Higashi syndrome (CHS), over 75 years ago, several studies have been conducted to underscore the role of the lysosomal trafficking regulator (LYST) gene in the pathogenesis of disease. CHS is a rare autosomal recessive disorder, which is caused by biallelic mutations in the highly conserved LYST gene. The disease is characterized by partial oculocut...
Source: Drug Discovery Today: Disease Models - Category: Drugs & Pharmacology Source Type: research
Cocco, Fabio / Cagetti, Maria Grazia / Livesu, Roberta / Camoni, Nicole / Pinna, Roberto / Lingstr öm, Peter / Campus, GuglielmoPage 515 - 522Purpose: To evaluate the effect of sugar-free snacks on caries-related factors in 6- to 9-year-old schoolchildren.Materials and Methods: Two hundred seventy-one children at risk for caries as measured through the Cariogram were randomly assigned to three groups consuming twice-daily snacks containing Stevia, maltitol or sugar for 42 days. Parents filled out a standardised questionnaire regarding personal, medical and oral behavioural information. Bleeding on probing, plaque pH a...
Source: Oral health and Preventive dentistry - Category: Dentistry Source Type: research
Publication date: Available online 9 December 2019Source: European Journal of Integrative MedicineAuthor(s): Xiao-Qing Wang, Pei-Bei Duan, Man Zheng, Qian Xu, Li-Hua Yang, A-Qin WangAbstractIntroductionAuricular acupuncture has been used for pain management. A more recent technique which buries an intradermal needle into the skin may provides long lasting stimulation and enhance analgesia. The purpose of this study was to evaluate the efficacy and feasibility of perioperative auricular acupuncture technique via intradermal needling buried on postoperative movement-evoked pain reduction of patients with advanced gastric can...
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
Conclusion: The data support the hypothesis that progressive LPT is associated with immunological findings that may serve as an initial screen for progressive LPT. PMID: 31814459 [PubMed - as supplied by publisher]
Source: Inhalation Toxicology - Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research
ConclusionsOur systematic review suggested that thermal ablation combined with cementoplasty could be a safe and effective intervention for the management of bone metastases-induced pain.
Source: Journal of Bone Oncology - Category: Cancer & Oncology Source Type: research
Authors: Torres M, Herrera MT, Fabián-San-Miguel G, Gonzalez Y Abstract Diabetes mellitus, a metabolic disease characterized by hyperglycemia and poor glucose control, is a risk factor for Mycobacterium tuberculosis (M. tuberculosis) infection and the development of active tuberculosis. To evaluate whether M. tuberculosis infection susceptibility is associated with an intrinsic factor in monocytes from type 2 diabetes (T2D) patients or it is associated with hyperglycemia per se, we analyzed TLR-2 and TLR-4 expression by flow cytometry and the cytokines IL-1β, IL-6, IL-8, IL-10, and TNF-α by cytome...
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
Publication date: April 2018Source: Case Reports in Women's Health, Volume 18Author(s): Ashima Arora, Shameema Anvar SadathAbstractGenital tuberculosis is usually diagnosed in young women being assessed for infertility. After menopause it usually presents with symptoms resembling endometrial malignancy, such as postmenopausal bleeding, persistent vaginal discharge and pyometra. The diagnosis is made by detection of acid-fast bacilli on microscopy or bacteriological culture and/or presence of epithelioid granuloma on biopsy. Anti-tubercular therapy involves the use of rifampicin, isoniazid, pyrazinamide and ethambutol. Surg...
Source: Case Reports in Womens Health - Category: OBGYN Source Type: research
More News: Bleeding | Cancer & Oncology | Endometrial Biopsy | Infertility | Men | Menopause | OBGYN | Pain | Reproduction Medicine | Tuberculosis | Weight Loss | Women