Colon signaling pathway key to inflammatory bowel disease

(Tokyo Medical and Dental University) Inflammatory bowel disease (IBD) develops because of an uncontrolled immune response in the colon. Japanese research led by Tokyo Medical and Dental University (TMDU) showed that a signaling pathway underlies the differentiation of white blood cells into a population capable of inducing inflammation. This signaling pathway also enhanced the expression of genes encoding inflammatory mediators, opening up the possibility of developing drugs to target these mechanisms in IBD therapy.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news