Lyme Endocarditis

We describe a case of Lyme endocarditis which, to our knowledge, is the first reported case confirmed by molecular diagnostics in the United States.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Brief Observation Source Type: research

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Publication date: Available online 21 May 2019Source: Journal of Environmental PsychologyAuthor(s): Emmy van Esch, Robert Minjock, Stephen M. Colarelli, Steven HirschAbstractA growing number of organizations are re-designing workplaces to give employees greater exposure to natural views, which frequently improve well-being. But what is it about views of nature that produce these benefits? Is it the overall view or the particular features within a view? If it is features, what features have the greatest effects on well-being, and are these features particular to natural settings or might they generalize to built settings? W...
Source: Journal of Environmental Psychology - Category: Psychiatry & Psychology Source Type: research
U.S. District Judge Virginia M. Kendall for the Northern District of Illinois entered a consent decree of permanent injunction today between the United States and PharMedium Services, LLC, headquartered in Lake Forest, Illinois.
Source: FDA Center for Drug Evaluation and Research - What's New - Category: Drugs & Pharmacology Authors: Source Type: news
In conclusion, we unraveled the secretome of G. adiacens, an oral bacterium well-documented in infective endocarditis, but also recently shown to be involved in oral infections. Importantly, the secretome of G. adiacens comprised of a large number of putative virulence factors. Of particular importance is the finding that the G. adiacens secretome comprised of a number of “moonlighting” proteins, which in other species are shown to enhance bacterial colonization and virulence through their multifunctional roles (Pavkova et al., 2017; Graf et al., 2019). Thus, our results provide a basis for investigating the ro...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
We describe a case of mitral regurgitation with a preoperative diagnosis of myxomatous mitral valve degeneration. During surgery, the surgeon suspected infective rather than degenerative; etiology; tissue cultures were negative. However, universal bacterial PCR on explanted valve tissue detected Borrelia burgdorferi Deoxyribonucleic Acid(DNA). If a surgeon suspects infective endocarditis at the time surgery, appropriate specimens should be sent for histopathology, culture, and PCR.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
We describe a case of mitral regurgitation with a preoperative diagnosis of myxomatous mitral valve degeneration. During surgery, the surgeon suspected infective rather than degenerative; etiology; tissue cultures were negative. However, universal bacterial PCR on explanted valve tissue detected Borrelia burgdorferi Deoxyribonucleic Acid(DNA). If a surgeon suspects infective endocarditis at the time surgery, appropriate specimens should be sent for histopathology, culture, and PCR. PMID: 30690018 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
Conclusions:Focal neurologic deficits are not a common early presentation of IE. The visual field cut in this case was typical for a retinal artery occlusion and represented an embolic event. The diplopiawas likely caused by the thalamic infarct, with involvement of the corticomesencephalic tract. In characteristic fashion for IE, time required for bacterial culture growth was lengthy. Prompt recognition of focal deficits in a patient with signs and symptoms of systemic inflammation may allow for earlier recognition of IE.Study Supported by:Disclosure: Dr. Stephens has nothing to disclose. Dr. Frattalone has nothing to disclose.
Source: Neurology - Category: Neurology Authors: Tags: Autoimmunity with Infection, Syphilis, Lyme, Tuberculosis, and other Bacteria Source Type: research
Conclusions:Antibiotic treatment for S. pneumoniae meningitis correlated with improvement in clinical status and TCD hemodynamics. Serial TCDs may be a potentially useful strategy in the management of bacterial meningitis.Disclosure: Dr. Idris has nothing to disclose. Dr. Tai has nothing to disclose. Dr. Tan has nothing to disclose. Dr. Tan has nothing to disclose.
Source: Neurology - Category: Neurology Authors: Tags: Autoimmunity with Infection, Syphilis, Lyme, Tuberculosis, and other Bacteria Source Type: research
Discussion Fatigue is a subjective feeling of decreased energy, tiredness or feeling of exhaustion. Lethargy is often used synonymously, but lethargy is a state of being drowsiness or sleepy, and implies mental status changes. Both can cause the person to be apathetic or less active. Fatigue is a common state that almost everyone experiences multiple times in his or her lifetime. For most people it is a relatively acute or short-term chronic problem, often with a relatively easily identifiable problem cause, such as inadequate sleep, acute illness, or overexertion. For some, it can be less readily identifiable such as dep...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Spring is my favorite season. Warmer weather, budding flowers and lots of greenery in yards, gardens and parks encourages outside activities and fills me with energy. The spring season also brings out lots of crawling and flying critters like bees, butterflies, and hummingbirds, as well as some of the more unpleasant pests like ticks and mosquitos. If you enjoy spending time outside like I do, hiking, gardening or walking the dog, be aware that ticks and their bites can be not only annoying, but dangerous. Jana’s Experience Jana Braden found out how dangerous tick bites can be the hard way. She enjoyed the outdoors a...
Source: Disruptive Women in Health Care - Category: Consumer Health News Authors: Tags: Chronic Conditions Source Type: blogs
CONCLUSIONS: In our series the most common reason for a positive broad-range PCR result was contamination. Unlike endocarditis, in suspected CNS infections broad-range PCR was not useful, probably because the etiologies are often viruses (which are not amenable to broad-range PCR) or non-infectious. CSF might not be the ideal specimen for intra parenchymal processes. Further research is needed to identify which syndromes and specimen source would be ideal for broad-range PCR in CNS infection.Disclosure: Dr. Koffman has nothing to disclose. Dr. Bernatowicz has nothing to disclose. Dr. Shrestha has nothing to disclose. Dr. B...
Source: Neurology - Category: Neurology Authors: Tags: Lyme and Other CNS Infections Source Type: research
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