Molecular characterization of fowl aviadenoviruses species D and E associated with inclusion bodies hepatitis in chickens and falcons indicates possible cross-species transmission.
Molecular characterization of fowl aviadenoviruses species D and E associated with inclusion bodies hepatitis in chickens and falcons indicates possible cross-species transmission. Avian Pathol. 2018 Mar 28;:1-20 Authors: Mohamed MH, El-Sabagh IM, Abdelaziz AM, Al-Ali AM, Alramadan M, Lebdah MA, Ibrahim AM, Al-Ankari AS Abstract During the period from 2015 to 2017, frequent outbreaks of inclusion body hepatitis (IBH) were observed in chicken broilers and falcons in Saudi Arabia. Fifty samples were collected from both species. The histopathological examination and PCR confirmed the IBH infection in eight samples (5 samples from chickens and 3 samples from falcons). The genomic sequence and phylogenetic analysis based on nucleotide and amino acids sequences of Saudi strains, reference fowl aviadenoviruses (FAdVs) and field viruses available in Genbank revealed that, all investigated FAdVs clustered into FAdV-2 (species D) and FAdV-6 (species E). The host-dependent characterization revealed that Falcon origin strains showed low identity (∼35%) with falcon adenoviruses (FaAdVs) isolated from USA, which clustered into a separate group. The identification of FAdV-D and FAdV-E in diseased falcons and chickens indicates cross-species transmission although; both falcons and chickens are phylogenetically different. The control of IBH infection in falcons and chickens should be based on the separation of carriers and susceptible chicken as well as falcons to pr...
Travel links to city shut down in bid to curb worst viral outbreak since Sars in 2003
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