Combination of resveratrol ‐containing collagen with adipose stem cells for craniofacial tissue‐engineering applications

International Wound Journal, EarlyView.
Source: International Wound Journal - Category: Surgery Source Type: research

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Date: Wednesday, 10 30, 2019; Speaker: Hyunsoo Shawn Je, Prof., Duke-NUS Medical School; Building: Building 5; 127
Source: NIH Calendar of Events - Category: American Health Source Type: events
Publication date: Available online 22 October 2019Source: Stem Cell ResearchAuthor(s): Jonathan Arias-Fuenzalida, Jingwei Yu, Likun Du, Joaquin Custodio, Luigi D. Notarangelo, Lennart Hammarström, Qiang Pan-HammarströmAbstractSelective immunoglobulin-A deficiency (IgAD) is the most common primary immunodeficiency (PID) in the Western world and results in higher susceptibility to infections, autoimmune disorders and malignancies. We generated human induced pluripotent stem cell lines from two patients with selective immunoglobulin-A primary immunodeficiency, PHAi001 and PHAi002. Patient samples were reprogrammed u...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Publication date: Available online 21 October 2019Source: Stem Cell ResearchAuthor(s): T.A. Shnaider, I.E. Pristyazhnyuk, A.G. Menzorov, N.M. Matveeva, A.A Khabarova, N.A. Skryabin, A.A. Kashevarova, M.E. Lopatkina, L.P. Nazarenko, I.N. Lebedev, O.L. SerovAbstractThe human induced pluripotent stem cell (iPSC) lines, ICGi009-A, ICGi009-B, ICGi013-A and ICGi013-B, were generated from skin fibroblasts of two siblings with intellectual disability. Both patients were carriers of CNTN6 gene microdeletion(Kashevarova et al., 2014). iPSC lines have normal karyotype, express pluripotency markers, are able to differentiate in vitro ...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Publication date: Available online 21 October 2019Source: Stem Cell ResearchAuthor(s): Haiyan Zhang, Yanyan Ma, Shujuan Yu, Xiaomeng Yang, Yue Li, Jingyun Guan, Rui Dong, Zhongtao Gai, Yi LiuAbstractWe established an induced pluripotent stem cell (iPSC) line (SDQLCHi010-A) from peripheral blood mononuclear cells isolated from a 4-year-old boy with optic nerve malformation and intellectual disability carrying a heterozygous mutation (c.220A>G (p.S74G)) in PAX6 gene. Non-integrating episomal vectors containing OCT4, SOX2, KLF4, BCL-XL and MYC were used for reprogramming. The established iPSC line showed normal karyotype, ...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Publication date: Available online 21 October 2019Source: Stem Cell ResearchAuthor(s): Chanchao Lorthongpanich, Nittaya Jiamvoraphong, Prapasri Supakun, Nattaya Damkham, Papussorn Terbto, Supaporn Waeteekul, Yaowalak U-pratya, Chuti Laowtammathron, Surapol IssaragrisilAbstractWWTR1 or TAZ (WWTR1/TAZ) is a transcriptional coactivator that acts as a downstream regulatory target in the Hippo signaling pathway, which plays a pivotal role in regulating cell proliferation and anti-apoptosis. It has been shown in other cell types that WWTR1/TAZ plays a redundant role to its homolog YAP1. Using CRISPR/Cas9 gene editing, we establi...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Publication date: Available online 21 October 2019Source: Stem Cell ResearchAuthor(s): Gabriele Louise Soares Martins, Bruno Diaz Paredes, Gabriela Louise de Almeida Sampaio, Carolina Kymie Vasques Nonaka, Katia Nunes da Silva, Kyan James Allahdadi, Milena Botelho Pereira Soares, Ricardo Ribeiro dos Santos, Bruno Solano de Freitas SouzaAbstractHuman-induced pluripotent stem cell (hiPSC) CBTCi001-A line was generated from a healthy 30-year old male dermal fibroblasts using non-integrative reprogramming method using episomal-based plasmids expressing OCT4, SOX2, KLF4, and MYCL. Characterization of CBTCi001-A was confirmed by...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Publication date: Available online 22 October 2019Source: Nanomedicine: Nanotechnology, Biology and MedicineAuthor(s): Muhammad Younis, Wang Faming, Zhao Hongyan, Tan Mengmeng, Song Hang, Yuan LiudiAbstractGlioma is the most common neoplasm of the central nervous system, with the highest mortality rate. The present study was designed to examine the therapeutic effect of Iguratimod (IGU) encapsulated- poly (lactic-co-glycolic acid) PLGA nanoparticles (IGU-PLGA-NPs), which showed inhibition of glioma cells proliferation both in vitro and in vivo. IGU was encapsulated in PLGA nanoparticles with an average size of 100-200 nm w...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
Conclusion: After exposure to primary physical or mental stressor, hair follicles are stimulated to enter prematurely into telogen and shed out. In individuals with Taq1 and Cdx1 polymorphisms, the disease persists as a result of prevention of new anagen growth and inhibition of hair follicle stem cell proliferation. PMID: 31632122 [PubMed]
Source: Clinical, Cosmetic and Investigational Dermatology - Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research
The architect of the 2004 ballot measure that created California's stem cell research funding initiative wants to put a $5.5 billion initiative on the November 2020 ballot.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
In this study, a type I collagen scaffold made from a recombinant peptide (RCP) with an Arg-Gly-Asp motif was developed, and its effect on regeneration in critical-size mandibular bone defects was evaluated. Additionally, the combined effect of the scaffold and lipid-free dedifferentiated fat (DFAT) cells was assessed. Briefly, DFAT cells were separated from mature adipocytes by using a ceiling culture technique based on buoyancy. A 3 cm × 4 cm critical-size bone defect was created in the rat mandible, and regeneration was evaluated by using RCP with DFAT cells. Then, cultured DFAT cells and adipose-derived stem cell...
Source: Journal of oral science - Category: Dentistry Tags: J Oral Sci Source Type: research
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