New diagnosis of bullous pemphigoid after withdrawal of immunosuppressive therapy in a failed renal transplant recipient on hemodialysis
Hemodialysis International, EarlyView.
Authors: Pezzolo E, Naldi L Abstract Introduction: "Chronic inflammatory immune-related skin disease" (ISDs) is an umbrella term grouping together heterogeneous entities characterised by chronic inflammation potentially involving the whole skin. We are not covering all ISDs in this review, but take a few as the most representative, including nonbullous and bullous diseases. The question we are aiming to address can be summarised as follows: "despite the differences, is it possible to define some unifying epidemiologic characteristics and shared progression pathways which can guide the organization of...
We report a case of PG in a woman whose pregnancy was achieved using egg donation. Since the entire fetal genome is allogeneic to the mother, augmented immune reaction in egg-donated pregnancies appears to trigger the occurrence of PG. PMID: 31950210 [PubMed - as supplied by publisher]
We present an 84y woman with a three week history of erythematous rash, and 48hrs of bullae. A left clear cell renal cell carcinoma was identified on CT imaging during the presentation. Subsequent removal of the tumour resulted in resolution of bullous pemphigoid symptoms. This first-of-kind case and successful result strengthens the association between renal cell carcinoma and paraneoplastic bullous pemphigoid, arguing for a high degree of clinical suspicion in unexplained presentations of bullous pemphigoid.
AbstractPemphigoid gestationis is a rare subepidermal bullous dermatosis of pregnancy, caused by the interaction of IgG1 auto-antibodies with 180 kD BP Antigen 2. This disease can lead to preterm delivery, but the neonate is affected in only 10% cases. The treatment of choice in pemphigoid gestationis is systemic corticosteroids.
Conclusion: Eczema is the most prevalent skin infection among the elderly population. Age, consumption of alcohol, usage of more than five medicines simultaneously and presence of co-morbidities are the main factors that are involved in better treatment outcomes of skin infections among study population. PMID: 31916477 [PubMed - as supplied by publisher]
Publication date: Available online 23 December 2019Source: Journal of Dental SciencesAuthor(s): Hou-Chiang Chou, Yu-Hsueh Wu, Chun-Pin Chiang, Ju-Hsuan Yang