Schizophrenia moderates the relationship between white matter integrity and cognition
Cognitive impairment is a primary feature of schizophrenia, with alterations in several cognitive domains appearing in the pre-morbid phase of the disorder. White matter microstructure is also affected in schizophrenia and considered to be related to cognition, but the relationship of the two is unclear. As interaction between cognition and white matter structure involves the interplay of several brain structures and cognitive abilities, investigative methods which can examine the interaction of multiple variables are preferred.
Source: Schizophrenia Research - Category: Psychiatry Authors: Luis F.S. Castro-de-Araujo, Mathew Allin, Marco M. Picchioni, Colm Mcdonald, Christos Pantelis, Richard A.A. Kanaan Source Type: research