Serum carcinoembryonic antigen trends for diagnosing colorectal cancer recurrence in the FACS randomized clinical trial.
CONCLUSION: Interpreting trends in CEA measurements instead of single CEA test results improves diagnostic accuracy for recurrence, but not sufficiently to warrant it being used as a single surveillance strategy to trigger further investigation. In the absence of a more accurate biomarker, monitoring trends in CEA should be combined with clinical, endoscopic and imaging surveillance for improved accuracy.
PMID: 29579327 [PubMed - as supplied by publisher]
Source: The British Journal of Surgery - Category: Surgery Authors: Shinkins B, Primrose JN, Pugh SA, Nicholson BD, Perera R, James T, Mant D Tags: Br J Surg Source Type: research
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