Review Examines Efficacy and Safety of Osteoporosis Drugs (FREE)

By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Bisphosphonates, denosumab, teriparatide, and raloxifene all reduce risk for fracture relative to placebo in women with osteoporosis, according to a federally commissioned systematic review …
Source: Physician's First Watch current issue - Category: Primary Care Source Type: news

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Condition:   Postmenopausal Osteoporosis Intervention:   Drug: Binosto 70Mg Effervescent Tablet Sponsors:   251 Hellenic Air Force & VA General Hospital;   Laikο General Hospital, Athens;   424 General Military Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Intriago M, Maldonado G, Guerrero R, Messina OD, Rios C Abstract Objective: To study the association between osteoporosis and sarcopenia and determine the prevalence of osteosarcopenia in patients who attended a rheumatology center in Ecuador. Methods: A cross-sectional study was conducted in a population of patients who had a densitometric study. The diagnosis of sarcopenia was determined by the DXA standard gold test, screening, and conventional methods (bioimpedance, anthropometric measurements, SARC-F, muscle function, and gait test). Results: A total of 92 patients were studied. The median age...
Source: Journal of Aging Research - Category: Geriatrics Tags: J Aging Res Source Type: research
As our population ages, there are many health care issues that emerge. It is well known that the elderly are more prone to polypharmacy and that prescribed drug-related issues among the US population have been more catastrophic for the elderly, with the exception perhaps of the matters associated with the opioid epidemic. More than half of the individuals who are over the age of 50 have some semblance of bone compromise, be it overall bone health, osteoporosis, or osteopenia. As the prevalence of these issues continues to rise, it is anticipated that fractures related to fragility will increase as the age of the population increases.
Source: Nursing Clinics of North America - Category: Nursing Authors: Tags: Foreword Source Type: research
AbstractPurpose of ReviewThe aim of this narrative review is to summarise recent literature on the effects of exercise and nutrition interventions alone or in combination on muscle and bone loss in people with cancer.Recent FindingsThere is emerging evidence to support the inclusion of targeted exercise and nutrition strategies to counter loss of muscle and bone associated with cancer treatments. Although research in this field is advancing, the optimal exercise and nutrition prescription to combat cancer-related bone and muscle loss remain unknown.SummaryThis review identifies specific components of nutrition and exercise...
Source: Current Osteoporosis Reports - Category: Orthopaedics Source Type: research
AbstractSummaryEffects on bone material properties of two-year antiosteoporotic treatment were assessed using in vivo impact microindentation (IMI) in patients with low bone mineral density (BMD)  values. Antiresorptive treatment, in contrast to vitamin D ± calcium treatment alone, induced BMD-independent increases in bone material strength index, measured by IMI, the magnitude of which depended on pretreatment values.IntroductionBone material strength index (BMSi), measured by IMI in vivo, is reduced in patients with fragility fractures, but there is no information about changes in values during long-term ther...
Source: Osteoporosis International - Category: Orthopaedics Source Type: research
ConclusionsThe EuBIVAS has provided updated BV estimates for bone markers, including iFGF23, which have not been previously published, facilitating the improved follow-up of patients being treated for metabolic bone disease.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research
ConclusionThis KPI set compliments the existing Best Practice Framework to support FLSs to examine their own performance using patient-level data. By using this KPI set for local quality improvement cycles, FLSs will be able to efficiently realise the full potential of secondary fracture prevention and improved clinical outcomes for their local populations.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research
Source: Clinical Interventions in Aging - Category: Geriatrics Tags: Clinical Interventions in Aging Source Type: research
In this study, we showed that osteoporosis is highly associated with reduction in hematopoietic autophagy activity in humans. We showed that an autophagy defect in the hematological system leads to severe bone loss. The disturbed osteocyte homeostasis is apparently caused by impaired type H blood vessels and possibly an aberrant alteration in the extracellular matrix (ECM) pathways that govern osteocyte homeostasis in hematopoietic autophagy-defective mice. Our results thus suggest that autophagy in the adjacent hematopoietic cells is essential to maintain bone homeostasis, and chronic hematopoietic autophagy deficiency ca...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
(Natural News) Fasting can improve reproductive and mental health, as well as lower the risk of musculoskeletal disorders in women, according to a recent review published in the Journal of Mid-Life Health. Researchers from the National Institute of Naturopathy in India found evidence that fasting not only prevents metabolic disorders, but it also improves bone health. The...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
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