Urinary Iron Excretion is Associated with Urinary Full-Length Megalin and Renal Oxidative Stress in Chronic Kidney Disease

Conclusions: Our findings suggest that renal iron handling may be associated with megalin-mediated endo-lysosomal metabolic load in PTECs of residual nephrons and oxidative stress in renal tubules.Kidney Blood Press Res 2018;43:458 –470
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research

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CONCLUSIONS: In the EXCEL trial, PCI of LM disease with TRA was associated with comparable early and late clinical outcomes as TFA. PMID: 30111521 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
Heatwaves have ravaged much of the northern hemisphere, causing wildfires, destruction and death. Some are blaming heat stress for an increase in chronic kidney disease in Central America.Graihagh Jackson investigates the causes and health effects of heatwavesSubscribe and review onAcast,Apple Podcasts,Soundcloud,Audioboom andMixcloud. Join the discussion onFacebook andTwitterHeatwaves have hit many parts of the northern hemisphere this summer, ravaging landscapes and causing death and destruction in their wake. Wildfires have broken out in the Arctic Circle, as well as inCalifornia,Sweden andGreece. People are dying from ...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Science Climate change Environment Weather Wildfires Source Type: news
Publication date: Available online 16 August 2018Source: Canadian Journal of CardiologyAuthor(s): Bryan J. Har, Matthew T. James
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Resumo A doen ça renal crônica (DRC) é complexa, exigindo múltiplas abordagens em seu tratamento. O objetivo do presente estudo foi avaliar o impacto de um programa de intervenção nutricional sobre o estado nutricional e a qualidade de vida de idosos com DRC não dialítica. Foi realizada uma coorte prospec tiva com 64 idosos, de ambos os sexos, com DRC estágio 3, atendidos em Unidade Básica de Saúde, em Diadema/SP. A intervenção nutricional consistiu em três encontros coletivos e um individual. O estado nutricional foi avaliado p...
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
Publication date: Available online 16 August 2018Source: American Journal of Kidney DiseasesAuthor(s): Maria L. Gonzalez Suarez, Andrea Kattah, Joseph P. Grande, Vesna GarovicAs the incidence of chronic kidney disease increases and women pursue pregnancy at more advanced ages, the management of kidney disease in pregnancy has become increasingly relevant to the practicing nephrologist. Women with kidney disorders face several challenges in pregnancy due to increased physiologic demands on the kidney and risk for disease progression, the potential teratogenicity of medications, and the increased risk for complications such ...
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
(Reuters Health) - Patients with chronic kidney disease could slow the progression of their illness and delay dialysis through nutrition therapy, according to a new article in the Journal of the Academy of Nutrition and Dietetics.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
In conclusion, our data demonstrated that JPYSF remarkably retards development and progression of CKD in a 5/6 Nx rat model, which may be associated with inhibition of inflammation via NF-κB signaling pathway. PMID: 30108662 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
In conclusion, these 2 c ases argue for increased awareness for the possibility of renal failure as a consequence of anti-VEFG treatment. Predisposing conditions like known mild chronic renal insufficiency with only mild proteinuria and with atherosclerosis or precipitating co-medications like zoledronate infusion need to b e accounted for to prevent these severe AEs.Eur Thyroid J
Source: European Thyroid Journal - Category: Endocrinology Source Type: research
Just 12 weeks of aerobic and strength-based exercise reduces symptoms and levels of fatigue in patients with chronic kidney disease, according to findings from a UK study.
Source: Nursing Times - Category: Nursing Source Type: news
A morbidly-obese 57-year-old diabetic and hypertensive man with chronic kidney disease, diastolic heart failure, and bilateral hearing loss was found to have soft tissue masses/densities in the lateral aspect of both auditory canals on local examination and on imaging. He underwent biopsies of both ear canal masses and histologic examination revealed amyloid deposits in the dermis. These deposits were confirmed as AL (amyloid light chain) kappa-type amyloid by laser mass spectrometry. A systemic work-up showed plasma cell dyscrasia with 9% kappa light chain restricted plasma cells in the bone marrow as well as amyloid depo...
Source: Otology and Neurotology - Category: ENT & OMF Tags: Temporal Bone Histopathology Case of the Month Source Type: research
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