Punicalagin ameliorates the elevation of plasma homocysteine, amyloid- β, TNF-α and apoptosis by advocating antioxidants and modulating apoptotic mediator proteins in brain.
In conclusion, punicalagin protected from methionine-induced HHcy and brain damage with an ability to repress apoptosis by modulating apoptotic mediators and maintaining DNA integrity in the brain of mice.
PMID: 29579708 [PubMed - as supplied by publisher]
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: El-Missiry MA, ElKomy MA, Othman AI, AbouEl-Ezz AM Tags: Biomed Pharmacother Source Type: research