Startup Turns to Liquified Silk for Tissue Regeneration
A Boston-area plastic surgery startup wants to use a reverse-engineered form of an ancient medical material in tissue regeneration for aesthetics and medical purposes. Sofregen is working on tissue regeneration using liquefied silk protein, which has emerged from academic research in recent decades. Liquefied silk protein offers biocompatibility and engineering controllability without using harsh chemicals, according to Sofregen chief medical officer Anh Hoang. Hear Anh Hoang discuss the use of silk protein in implantable devices on April 18, 2018, at BIOMEDevice Boston. Use promo code "MDDI" for 20% off conference registration and free expo access. “It’s already used in sutures and mesh,” Hoang said. “We can control how much protein content there is. We can control the mechanics of it.” Silk has been used in medical applications for about 2,000 years, but the first mass-produced, sterile silk sutures were invented by Johnson &Johnson in 1887. Working with technology developed at Tufts University and the University of Pittsburgh, Sofregen is developing a silk scaffold that can be injected to provide immediate bulking of tissue and eventually help it regenerate. It has applied for FDA approval. The first indication would be to bulk up vocal folds so they can come together to produce the sounds used for speech. After the initial bulking, the silk scaffold would be replaced by the patient’s own tissue over the course of 2...
ConclusionsA history of asthma or sinonasal disease may modulate immunological response to reduce incidence of active TB in the adult population.
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ConclusionAllergy skin tests are reliable and justified for diagnosing allergies in cases of persistent or recurrent oral diseases. This is the only way to confirm allergies and is the basis for consequent allergen avoidance for the benefit of the patient.
NIH oversight panel no longer plans to review all applications for gene therapy experiments
CONCLUSION: It is concluded that nutraceuticals possess enormous health benefits and their interventions can be highly beneficial in the prevention/reduction of CVDs and related disorders such as atherosclerosis, hypertension, heart attack and stroke. The findings of this review provide an update on the emerging uses of nutraceuticals, functional foods, and herbal remedies in humans. Nevertheless, large-scale randomized, placebo-controlled, double-blind clinical trials are needed to confirm the health benefit claims about nutraceuticals and herbal products to establish their long-term safety and to resolve the controversy ...
Worsening seen for sleep duration, quality of sleep, and daytime sleepiness
Condition: Allergic Rhinitis Intervention: Other: e-BOOK Sponsor: Assistance Publique Hopitaux De Marseille Not yet recruiting
Condition: HIV Infections Interventions: Drug: Standard of Care (SOC) Oral ART; Drug: Oral RPV; Drug: Oral CAB; Drug: RPV-LA Loading Dose; Drug: CAB-LA Loading Dose; Drug: RPV-LA Maintenance Dose; Drug: CAB-LA Maintenance Dose Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting
NBCNews: The generic of the lifesaving allergy medication will offer a cheaper alternative to the Mylan’s EpiPen, which has come under fire for massive price hikes. Bystander Epinephrine in Community Anaphylaxis Critical Updates in Assessment &Management of Anaphylaxis Treat Anaphylactic Incidents Before it’s Too Late
The Food and Drug Administration Thursday approved a new generic version of the EpiPen, a move that could drive down the price and increase the availability of the emergency allergy medication auto-injector. The generic version will be made by Teva Pharmaceuticals USA (NYSE:TEVA) in 0.3 mg and 0.15 mg strengths, the New York Times reported. EpiPen manufacturer Mylan has c ome under intense criticism for raising the price of the medication, which is used by people with severe allergies to prevent…