Elevated Urine Levels of Macrophage Migration Inhibitory Factor in Inflammatory Bladder Conditions: a Potential Biomarker for a Subgroup of Interstitial Cystitis/Bladder Pain Syndrome Patients

(1) Objectives: To investigate whether urinary levels of macrophage migration inhibitory factor (MIF) are elevated in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) patients with Hunner lesions and also whether urine MIF is elevated in other forms of inflammatory cystitis. (2) Methods: Urine samples were assayed for MIF by ELISA. Urine samples from three female groups were examined: IC/BPS patients without (N=55) and with Hunner lesions (N=43); Non-IC/BPS patients (N=100; control group; no history of IC/BPS; cancer or recent bacterial cystitis).
Source: Urology - Category: Urology & Nephrology Authors: Tags: Female Urology, Urodynamics, Incontinence, and Pelvic Floor Reconstructive Surgery Source Type: research