Cytotoxic activity of abietane diterpenoids from roots of Salvia sahendica by HPLC-based activity profiling

This study reveals that the HeLa cells are more sensitive to all tested compounds than the Caco-2 cells. In silico molecular docking study showed a rigid binding of the compounds to tyrosine kinase pp60src, and proved their cytotoxic activity.
Source: Revista Brasileira de Farmacognosia - Category: Drugs & Pharmacology Source Type: research