Autism risk: Obese mothers run a 65 per cent greater risk of having a child with autism

PREGNANT women who are overweight before they conceive run a 65 per cent greater risk of having a baby with autism, research suggests.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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AbstractObjectiveTo evaluate the long-term pediatric neuropsychiatric morbidity of children born to obese patients.Study designA population-based cohort analysis was performed comparing all deliveries of obese (maternal pre-pregnancy body mass index of 30  kg/m2 or more) and non-obese patients between 1991 and 2014 at a single tertiary medical center. Hospitalizations of the offspring up to the age of 18  years involving neuropsychiatric morbidities were evaluated according to a pre-defined set of ICD-9 codes, including autistic, eating, sleeping and movement disorders, cerebral palsy, developmental disorders, an...
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
ConclusionOur findings support increased paternal BMI negatively affecting pregnancy and child health outcomes. Future studies must include or adjust for paternal contributions, as the longstanding assumption that only maternal factors are relevant is likely to have considerably confounded prior work.
Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
Authors: Brodowski L, Büter W, Kohls F, Hillemanns P, von Kaisenberg C, Dammann O Abstract Maternal overweight and obesity are prenatal risk factors for obstetrical complications, preterm birth, neonatal morbidity as well as cognitive and behavioural developmental disorders in children. Paediatric morbidity and mortality as well as child development disorders are significantly associated with maternal obesity. Particularly in the neurodevelopmental and psychiatric area, it is becoming increasingly clear that, in children of mothers with an increased body mass index (BMI), there is a high correlation with child...
Source: Geburtshilfe und Frauenheilkunde - Category: OBGYN Tags: Geburtshilfe Frauenheilkd Source Type: research
We examined small study effects and excess significance. We did analyses under credibility ceilings. This review is registered with PROSPERO, number CRD42018091704.Findings46 eligible articles yielded data on 67 environmental risk factors (544 212 cases, 81 708 787 individuals) and 52 biomarkers (15 614 cases, 15 433 controls). Evidence of association was convincing for maternal age of 35 years or over (relative risk [RR] 1·31, 95% CI 1·18–1·45), maternal chronic hypertension (odds ratio [OR] 1·48, 1·29–1·70), maternal gestational hypertension (OR 1·37,...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 15 March 2019Source: Neurochemistry InternationalAuthor(s): Roger Maldonado-Ruiz, Lourdes Garza-Ocañas, Alberto CamachoAutism spectrum disorder (ASD) is a complex neurodevelopmental disease which involves functional and structural defects in selective central nervous system (CNS) regions harming capability to process and respond to external stimuli. In addition to genetic background, etiological causes of ASD have not been fully clarified. Maternal immune activation (MIA) during pregnancy have been proposed as a potential etiological cause leading to aberrant synaptic pruning and m...
Source: Neurochemistry International - Category: Neuroscience Source Type: research
ASD half as likely in high-risk children if mothers took prenatal vitamins during first month Related items fromOnMedica MHRA tightens licence restrictions on valproate for women Caffeine in pregnancy linked to risk of child overweight Valproate in pregnancy linked to raised autism risk Hunt announces Medicines and Medical Devices Safety Review Most CCGs missing smoking target for pregnant women
Source: OnMedica Latest News - Category: UK Health Source Type: news
AbstractStudies have examined the association between parental body mass index (BMI) and autism spectrum disorder (ASD) in offspring, with inconsistent results, especially regarding maternal obesity, overweight and underweight. Cochrane Library, EMBASE, PubMed and PsycINFO databases were searched up to March 2018 for relevant observational studies with no language restriction. Our literature search identified 13 eligible studies for meta-analysis (involving 943,293 children and 30,337 cases). For maternal BMI (13 studies), both maternal obesity [OR 1.41 (95% CI 1.19 –1.67)] and maternal overweight [OR 1.16 (95% CI 1....
Source: European Child and Adolescent Psychiatry - Category: Psychiatry Source Type: research
Obese, pregnant women with diabetes are more likely to have children with psychiatric disorders, such as ADHD or autism, according to a study published inPediatrics.Reuters
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
(Reuters Health) - Pregnant women who have both severe obesity and diabetes may be more likely to have children with autism, ADHD and other psychiatric disorders than mothers who don't have either condition during pregnancy, a new study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
(Natural News) Being obese before getting pregnant has been found to increase the chance of having a child with autism, according to a study. The study, conducted by researchers at Northwestern University, found that mothers whose waists were at least 80 centimeters (cm) before pregnancy had a 65 percent higher chance of giving birth to a child...
Source: - Category: Consumer Health News Source Type: news
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