Cystic fibrosis sputum rheology correlates with both acute and longitudinal changes in lung function.

CONCLUSIONS: Among these subjects with CF, there is a striking identity of the slope defining the relationship between ln Gꞌ or ln G" and FEV1. There are dramatic increases in dynamic viscosity and elasticity during a pulmonary exacerbation with return to baseline at recovery. This suggests that sputum viscoelastic properties are tightly associated with lung function and disease status.
PMID: 29559310 [PubMed - as supplied by publisher]

Source: Chest - March 17, 2018 Category: Respiratory Medicine Authors: Ma JT, Tang C, Kang L, Voynow JA, Rubin BK Tags: Chest Source Type: research