Notch1 and osteoblasts play role in bone cancer initiation

(Baylor College of Medicine) A new mouse model of osteogenic sarcoma, a potentially deadly form of bone cancer, shows that high levels of Notch1, a gene that helps determine cell fate, can drive osteoblasts, cells that normally lead to bone formation, to become cancerous, said researchers from Baylor College of Medicine in a report in the journal Cancer Cell.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news