Live bee sting acupuncture is deadly for Madrid woman

Once a month for two years, a 55-year-old woman in Madrid had gone for acupuncture therapy using live bee stings. Apitherapy -- the medicinal use of bee hive products, including honey, pollen and bee venom -- was the woman's go-to treatment for stress and contractures, a tightening of her muscles that caused stiff joints.
Source: - Health - Category: Consumer Health News Source Type: news

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Org. Biomol. Chem., 2019,17,1869-1874 DOI: 10.1039/C8OB01798K, PaperJihyun Hwang, Taeho Kang, Janghyun Lee, Byong-Seok Choi, Sunkyu Han A strategy to diversely functionalize the C7-position of DMXAA has been developed as a means to discover potential human-STING agonists. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research
Publication date: Available online 12 February 2019Source: Aggression and Violent BehaviorAuthor(s): Kennedy Mkutu, Tessa Rhodes Mkutu
Source: Aggression and Violent Behavior - Category: Psychiatry & Psychology Source Type: research
This fascinating open access paper investigates a role in aging for DNA fragments that have escaped the cell nucleus, for underlying reasons probably related to stochastic nuclear DNA damage, but yet to be comprehensively explored. They may contribute to cellular senescence and the chronic inflammation generated by senescent cells, and this is accomplished by activating an innate immune sensor, cGAS-STING. This innate immune mechanism is already strongly linked to the bad behavior of senescent cells. The most interesting portion of the work here is the prospect for cleaning up extranuclear DNA fragments via some form of mo...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
The cyclic GMP-AMP synthase/stimulator of IFN genes (cGAS/STING) pathway detects cytosolic DNA to activate innate immune responses. Poly(ADP-ribose) polymerase inhibitors (PARPi) selectively target cancer cells with DNA repair deficiencies such as those caused by BRCA1 mutations or ERCC1 defects. Using isogenic cell lines and patient-derived samples, we showed that ERCC1-defective non–small cell lung cancer (NSCLC) cells exhibit an enhanced type I IFN transcriptomic signature and that low ERCC1 expression correlates with increased lymphocytic infiltration. We demonstrated that clinical PARPi, including olaparib and r...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
The Boston firm, which previously developed STING activators for cancer immunotherapy, now plans to tackle the same drug target for different diseases
Source: Chemical and Engineering News - Category: Chemistry Authors: Source Type: research
I’m a science journalist by day, a photographer, dog walker and beer drinker most of the time I’m away from my desk, and a musician by night… That is to say, I earn my living writing about science, I take lots of photos, drink a few pints, and sing and play in a couple of bands, including C5, and a choir (BigMouth). You can hear my latest solo and collaborative recorded music on SoundCloud and BandCamp (two additional bc channels Sciencebass and my most recent productions on davebradley (latest mini-album online now “Bridge of Sighs”. Dave Bradley performing...
Source: David Bradley Sciencebase - Songs, Snaps, Science - Category: Science Authors: Tags: Music album dave bradley guitar Source Type: blogs
(Michigan State University) Publish or perish is an adage with particular sting for women and other underrepresented scholars prone to not getting deserved credit on scientific papers. F&W scientists will provide perspective and pointers at the upcoming AAAS Annual Meeting.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
Authors: Placinta IA, España-Gregori E, Rodrigo-Hernández A, Martínez-Rubio C, Safont-Albert J, Bort-Martí MÁ Abstract An 80 year-old woman with no relevant medical history, consulted for worsening of right palpebral itching and pain after an insect bite. Her eyelids had areas of laceration due to scratching, which rapidly progressed to fibrinoid necrosis over the first 24hours. Lesions were cultivated, revealing Streptococcus pyogenes and Staphylococcus aureus. The patient was admitted to hospital with the diagnosis of periorbital necrotising fasciitis, in order to receive treatm...
Source: Archivos de la Sociedad Espanola de Oftalmologia - Category: Opthalmology Tags: Arch Soc Esp Oftalmol Source Type: research
(MedPage Today) -- Clinicians accused, convicted, or under investigation
Source: MedPage Today Psychiatry - Category: Psychiatry Source Type: news
Updated Date: Feb 8, 2019 EST
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
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