Talking to God in the Walls: Prolonged Psychosis Associated with Left Insular Stroke

We describe a 74-year old Caucasian man with a medical history of ESRD status post renal transplant, admitted for a 4-month history of worsening, abrupt-onset psychosis. Initial treatment with several different antipsychotics was unsuccessful. An extensive medical evaluation including multiple Neurology consultations was unrevealing. Cerebrospinal fluid and paraneoplastic panel were negative. No malignancy was identified. Head MRI revealed an area of T2 hyperintensity in the left insular region.
Source: Psychosomatics - Category: Psychiatry & Psychology Authors: Source Type: research