Seizures in children with neurofibromatosis type 1: is neurofibromatosis type 1 enough?

ConclusionsOur results suggest seizures are more frequent in NF1 children (4.3%) than in general pediatric population (0.3 –0.5%) and that are someway related to NF1 in half of patients. Facing seizures in NF1, the clinician should first exclude brain tumors but also other, and rarer NF1-related scenarios, such as hydrocephalous and vasculopathies. Children with non-structural seizures frequently had a family history of epilepsy, raising questions about the pathogenic role of NF1. They should be approached as for the general population.
Source: Italian Journal of Pediatrics - Category: Pediatrics Source Type: research