UNC119 promotes the growth and migration of hepatocellular carcinoma via Wnt/ β/catenin and TGF/β-EMT signaling pathways.

CONCLUSION: UNC119 was significantly up-regulated in liver cancer cells and tissues. It promoted cell growth and migration through the Wnt/β-catenin and TGF-β/EMT signaling pathways, respectively. The anti-UNC119 treatment inhibited tumor cell proliferation, growth, migration and invasion by inhibiting the Wnt/β-catenin and GF-β/ EMT signaling pathways, respectively. PMID: 29552782 [PubMed - in process]
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research