Hyperbaric Oxygen Therapy as an Adjunct for Treating an Individual with Poorly Healing Bilateral Mandibular Fractures Suspect of Developing Towards Osteomyelitis: A Case Report and Clinical Experience.
Conclusion: The patient completed 30 hyperbaric oxygen treatments and 30 d of intravenous antibiotics. Clinically, the patient responded well and showed healed intraoral wounds and an objective decrease in erythrocyte sedimentation rate over the course of treatment. Unfortunately, on serial imaging the patient showed to have fibrous non-bony union of left fracture site. Even though the patient will need a final definitive plate for his fracture, it will be performed from an extraoral approach with no evidence of underlying infection. PMID: 29546339 [PubMed - as supplied by publisher]
Publication date: Available online 29 May 2020Source: Carbohydrate PolymersAuthor(s): Noha Hesham Radwan, Maha Nasr, Rania A.H. Ishak, Nourtan F. Abdeltawab, Gehanne A.S. Awad
Conclusion: This systematic review and meta-analysis will provide a comprehensive summary and careful evaluation of rifampicin as an adjuvant treatment of DFO with a view to providing multiple options for clinical treatment of the disease. Registration number: is INPLASY202040084.
The objective of this study is to identify the various neck spaces involved in skull base osteomyelitis, correlate them with the possible source of infection and identify the related complications.
AbstractAmidst the opioid overdose crisis, there are increased efforts to expand access to medications for opioid use disorder (MOUD). Hospitalization for the complications of substance use in the United States (US) provides an opportunity to initiate methadone, buprenorphine, and extended release naltrexone and link high-risk, not otherwise engaged, patients into outpatient care. However, treatment options for patients are quickly exhausted when these medications are not desired, tolerated, or beneficial. As an example, we discuss the case of a man who was hospitalized 27 times over 2 years for complications related...
CONCLUSIONS: The average patient is middle aged (often male) with a history of subacute back pain, sometimes presenting fever and/or neurological damage on diagnosis. Acute phase reactants are frequently raised. Diabetes mellitus, endocarditis and immunosuppressed patients may have the worst chance of a good outcome, therefore these patients should be more carefully managed (always try to obtain an imaging-guided biopsy, correct antibiotic treatment, and a functional and clinical follow-up). PMID: 32446680 [PubMed - as supplied by publisher]
ConclusionsBioabsorbable Mg and titanium screws had similar therapeutic efficacy in MM fracture fixation regarding functional and radiological outcomes. However, the rate of implant removal was higher with titanium screws. Bioabsorbable Mg screws may be a favorable fixation option since secondary implant removal procedures can be prevented.Level of evidenceLevel IV, Retrospective case series.
illalona RM, Muñoz-Molina GM PMID: 32456800 [PubMed - as supplied by publisher]
Infections after tibia fracture are one of the most challenging areas of orthopedic care. Specialized techniques are required to achieve resolution of the infection and bony union. We detail here our strategies for infection debridement, temporary skeletal stabilization, antibiotic administration, and definitive reconstruction. Special emphasis is on the treatment of osteomyelitis of the tibial shaft; however, these same techniques can be applied to other areas of the skeleton as well.
Small, Volume 16, Issue 20, May 22, 2020.
This study has revealed that SpoVG can modulate cell aggregation by repressing sasC expression and eDNA release. Furthermore, we have demonstrated the potential linkage between cell aggregation and antibiotic resistance. Our findings provide novel insights into the regulatory mechanisms of SpoVG involved in cell aggregation, biofilm development and formation in Staphylococcus aureus. PMID: 32444467 [PubMed - as supplied by publisher]