Hormone replacement therapy can boost brain and stop memory loss

A seven-year US study has found women who take HRT experience fewer age-related changes to the brain and fewer of them had an accumulation of toxic proteins linked to Alzheimer's Disease.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Middle-aged and worried about your memory slips? You probably don’t have dementia. The majority of the memory slips that concern this age group, and even those significantly older, are due to stress and other factors rather than impending dementia. However, researchers have now found that people who are suffering from memory loss but are unaware of their problem are most likely developing the disease. Read the full article on HealthCentral about awareness and memory loss - and how lack of  this awareness can point to developing dementia: MedicareFAQ – Medicare Resource Center Support a caregiver or jump-st...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
Molecules, Vol. 23, Pages 2663: Design, Synthesis of N-phenethyl Cinnamide Derivatives and Their Biological Activities for the Treatment of Alzheimer’s Disease: Antioxidant, Beta-amyloid Disaggregating and Rescue Effects on Memory Loss Molecules doi: 10.3390/molecules23102663 Authors: Tian Chai Xiao-Bo Zhao Wei-Feng Wang Yin Qiang Xiao-Yun Zhang Jun-Li Yang Gx-50 is a bioactive compound for the treatment of Alzheimer’s disease (AD) found in Sichuan pepper (Zanthoxylum bungeanum). In order to find a stronger anti-AD lead compound, 20 gx-50 (1–20) analogs have been designed and syn...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
This study was conducted to assess if curcumin prevents retrieval deficit induced by scopolamine in passive avoidance task. Moreover, according to the proposed link between cholinergic system and Akt/GSK-3β (Glycogen synthase kinase 3 beta) signaling, the hippocampal contents of these proteins were determined. Male NMRI mice (20-25g body weight) were treated with 50 or 100mg/kg/po curcumin or its vehicle for 10 days. On day 10, the animals were trained in passive avoidance apparatus. The retention trial was performed 24h later. Scopolamine (1mg/kg/i.p.) or its vehicle was administered 30min before retention test. At t...
Source: European Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Eur J Pharmacol Source Type: research
Abstract Based on the quantitative structure-activity relationship (QSAR), some novel p-aminobenzoic acid derivatives as promising cholinesterase enzyme inhibitors were designed, synthesized, characterized and evaluated to enhance learning and memory. The in vitro enzyme kinetic study of the synthesized compounds revealed the type of inhibition on the respective acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. The in vivo studies of the synthesized compounds exhibited significant reversal of cognitive deficits in the animal models of amnesia as compared to standard drug donepezil. Further, the...
Source: Bioorganic Chemistry - Category: Chemistry Authors: Tags: Bioorg Chem Source Type: research
Abstract BACKGROUND: Presence of blood brain barrier is one of the major hurdle in drug delivery to brain for the treatment of neurological diseases. Alternative and more effective drug delivery approaches have been investigated for the drug targeting to brain in therapeutic range. OBJECTIVE: The present investigation was carried out to improve the galantamine bioavailability in brain by intranasal drug delivery through thiolated chitosan nanoparticles and compared to nasal and oral delivery of its solution using pharmacodynamic activity as well as biochemical estimation. METHOD: Thiolated chitosan (modi...
Source: Current Drug Delivery - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Deliv Source Type: research
AbstractAccording to the recent study, world-wide 40 million patients are affected by Alzheimer disease (AD) because it is one of the dangerous neurodegenerative disorders. This AD disease has less symptoms such as short term memory loss, mood swings, problem with language understanding and behavioral issues. Due to these low symptoms, AD disease is difficult to recognize in the early stage. So, the automated computer aided system need to be developed for recognizing the AD disease for minimizing the mortality rate. Initially, brain MRI image is collected from patients which are processed by applying different processing s...
Source: Journal of Medical Systems - Category: Information Technology Source Type: research
AbstractFrom prehistoric time till today herbal medications are supposed to have neuroprotective effects both by inhibiting acetyl cholinesterase enzyme or antioxidant ability and are also affordable. Thus extensive studies are necessary to investigate the pharmacological effects of herbal plants. The goal of the present study was to ascertain the outcome ofNelumbo nucifera fruit (NNF) on scopolamine induced amnestic rats along with motor coordination in mice in order to explore its pharmacological use in disorders like Alzheimer ’s disease (AD). The effect of NNF on learning and memory was assessed by Morris water m...
Source: Metabolic Brain Disease - Category: Neurology Source Type: research
I started to think of my mother as deeply forgetful, not as an Alzheimer ’s patient.By Bob DeMarcoAlzheimer's Reading RoomI was interviewed by Lori La Bey on Alzheimer's Speaks Radio. I had no real expectation going into the interview. I should have known better.Lori caught me off guard when she asked me right up front to explain my construct of the deeply forgetful.Article -What is the Difference Between Alzheimer ’s and DementiaLater in the day I realized I really couldn't remember what I said. I went back and listened to my own words. I surprised myself while listening.Topic -How to Embrace Reality in Dement...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: activity director alzheimer's alzheimer's care care of dementia patients deeply forgetful dementia care health lifestyle memory care memory care facility nursing home Source Type: blogs
This study indicates that as the U.S. population increases, the number of people affected by Alzheimer ’s disease and related dementia will rise, especially among minority populations.Early diagnosis is key to helping people and their families cope with loss of memory, navigate the health care system, and plan for their care in the future. ” ~ saidCenter for Disease Control and Prevention Director Robert R. Redfield, M.D.How to Test Your Memory for Alzheimer's and Dementia (5 Best Tests)Racial disparities in future number of Alzheimer ’s patientsAlzheimer ’s disease is the fifth most common cause of...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer's disease facts Alzheimer's statistics caregtivers cdc center for disease control dementia health research Source Type: blogs
This article originally appeared on Kaiser Health News (KHN), a nonprofit news service covering health issues. It is an editorially independent program of the Kaiser Family Foundation that is not affiliated with Kaiser Permanente.
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized medicine Source Type: news
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