Hormone replacement therapy can boost brain and stop memory loss

A seven-year US study has found women who take HRT experience fewer age-related changes to the brain and fewer of them had an accumulation of toxic proteins linked to Alzheimer's Disease.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Authors: Solana C, Tarazona R, Solana R Abstract Alzheimer's disease (AD) represents the most common cause of dementia in the elderly. AD is a neurodegenerative disorder characterized by progressive memory loss and cognitive decline. Although the aetiology of AD is not clear, both environmental factors and heritable predisposition may contribute to disease occurrence. In addition, inflammation and immune system alterations have been linked to AD. The prevailing hypothesis as cause of AD is the deposition in the brain of amyloid beta peptides (Aβ). Although Aβ have a role in defending the brain against inf...
Source: International Journal of Alzheimers Disease - Category: Geriatrics Tags: Int J Alzheimers Dis Source Type: research
In conclusion, vitamin E can compensate the neuronal loss in the hippocampal formation and also it can raise the density of M1 receptor-ir muscarinic neurons after an injection of scopolamine. PMID: 30509043 [PubMed - in process]
Source: Folia Neuropathologica - Category: Pathology Authors: Tags: Folia Neuropathol Source Type: research
Authors: Shahmohamady P, Eidi A, Mortazavi P, Panahi N, Minai-Tehrani D Abstract The present study aimed to elucidate the neuroprotective effect of sinapic acid on intracerebroventricular streptozotocin (ICV-STZ) induced neuronal loss and memory impairment. To test this hypothesis, male Wistar rats were randomly divided into 11 groups: normal control, sham-operated control, sinapic acid (2.5, 5, 10, and 20 mg/kg bw intragastrically, daily) alone, Alzheimer control rats (ICV-STZ, 3 mg/kg bw), sinapic acid (2.5, 5, 10, and 20 mg/kg bw intragastrically, daily) together with STZ, and the treatment was performed accordi...
Source: Polish Journal of Pathology - Category: Pathology Tags: Pol J Pathol Source Type: research
Title: Health Tip: What Causes Memory Loss?Category: Health NewsCreated: 12/4/2018 12:00:00 AMLast Editorial Review: 12/4/2018 12:00:00 AM
Source: MedicineNet Alzheimer - Category: Geriatrics Source Type: news
Abstract The world's population continues to age at a rapid pace. By the year 2050, individuals over the age of 65 will account for sixteen percent of the world's population and life expectancy will increase well over eighty years of age. Accompanied with the aging of the global population is a significant rise in non-communicable diseases (NCDs). Neurodegenerative disorders will form a significant component for NCDs. Currently, dementia is the 7th leading cause of death and can be the result of multiple causes that include diabetes mellitus, vascular disease, and Alzheimer's disease (AD). AD may represent at leas...
Source: Current Neurovascular Research - Category: Neurology Authors: Tags: Curr Neurovasc Res Source Type: research
AbstractCognitive decline and memory impairment induced by oxidative brain damage are the critical pathological hallmarks of Alzheimer ’s disease (AD). Based on the potential neuroprotective effects of melatonin, we here explored the possible underlying mechanisms of the protective effect of melatonin against scopolamine-induced oxidative stress-mediated c-Jun N-terminal kinase (JNK) activation, which ultimately results in synapt ic dysfunction, neuroinflammation, and neurodegeneration. According to our findings, scopolamine administration resulted in LPO and ROS generation and decreased the protein levels of antioxi...
Source: Journal of NeuroImmune Pharmacology - Category: Drugs & Pharmacology Source Type: research
This study is the culmination of a decade of research that has repeatedly demonstrated that this vaccine can effectively and safely target in animal models what we think may cause Alzheimer’s disease. I believe we’re getting close to testing this therapy in people.” ~ said Dr. Roger Rosenbe rg, founding Director of the Alzheimer’s Disease Center at UT Southwestern.What is the Difference Between Alzheimer ’s and DementiaThe study was conducted by the UT Southwestern ’s Peter O’Donnell Jr. Brain Institute.Subscribe to the Alzheimer's Reading RoomEmail:A DNA vaccine tested in mice red...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer's research alzheimers Beta Amyloid dementia dna health memory memory loss science tau vaccine Source Type: blogs
Title: Health Tip: Should You Be Worried About Memory Loss?Category: Health NewsCreated: 11/21/2018 12:00:00 AMLast Editorial Review: 11/21/2018 12:00:00 AM
Source: MedicineNet Alzheimer - Category: Geriatrics Source Type: news
Alzheimer's and dementia patients often eat less, and have difficulty eating, because of problems like chewing, swallowing or digesting food.Alzheimer's and dementia patients sometimes lose interest in eating. This can happen for a long list of reasons including loss of taste, the ability to smell, memory loss, and thinking they already ate.Medications can also effect appetite, and can increase constipation.When a person has Alzheimer's disease or a related dementia, these problems can becomemore pronounced, and often effect mood, behavior, and physical functioning.Topic -How to Get an Alzheimer's Patient to Eat More FoodB...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: assisted living and memory care facility care of dementia patients dementia care dementia patients refusing to eat do people with Alzheimer's forget they ate help alzheimer's senior care Source Type: blogs
Ginkgo biloba extract, derived from the leaves of the Ginkgo biloba tree, is often touted as a memory aid. But it appears unlikely that Ginkgo biloba extract can slow or prevent age-related memory problems, or memory loss associated with mild cognitive impairment or Alzheimer's disease. Several small, early studies showed modest improvements in cognitive function [...]
Source: News from Mayo Clinic - Category: Databases & Libraries Source Type: news
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