Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas

In conclusion, a pronounced difference in sirtuins expression was identified between pituitary adenomas, suggesting that these genes are potential markers of pituitary adenomas and could be employed in the characterization of somatotropinomas and NFPAs. The role of sirtuins in pathogenesis of pituitary tumors merits further investigation and possibly will provide new molecular insight about their progression.
Source: Pituitary - Category: Endocrinology Source Type: research