More Cases Are Reported of Unusual Cancer Linked to Breast Implants
Women with breast implants have an increased risk of a type of lymphoma that can usually be cured by surgery alone — but not always.
ConclusionA DTF-specific HRQL tool and consensus regarding the preferred measurement tool among DTF patients is lacking. Our study indicates that HRQL of DTF patients was negatively affected in several domains. A DTF-specific HRQL measure could improve our understanding of short- and long-term effects and, ideally, can be used in both clinic and for research purposes.
Authors: Vajaitu C, Draghici CC, Solomon I, Lisievici CV, Popa AV, Lupu M, Caruntu C, Constantin MM, Voiculescu VM Abstract An important function of the immune system is its ability to differentiate between healthy cells in the organism and "foreign" cells, allowing the latest to be attacked and the first ones to be conserved. The most important molecules in this process are considered to be checkpoint inhibitors. This review is focused on the association between cancer and inflammation, underlying the mechanisms of action of monoclonal antibodies that are targeting checkpoint inhibitors: ipilimumab again...
CONCLUSIONS: Acknowledging the limitations of a retrospective analysis, our study confirms previous real-world evidence suggesting that continuing advances in the treatment of mRCC has led to improved outcomes in everyday practice worldwide. Pharmacoeconomic analyses are important for cost effective utilization of emerging novel therapies. PMID: 30417707 [PubMed - as supplied by publisher]
Authors: Zhou J, Zheng S, Liu T, Liu Q, Chen Y, Ma R, Tan D, Lu X Abstract Although M2 tumour-associated macrophages (M2 TAMs) have been shown to be associated with the progression and metastasis of breast cancer, their role in oesophageal squamous cell carcinoma (ESCC) remains less well understood. Therefore, to understand the clinicopathological significance of infiltrated M2 TAMs in ESCC, statistical analysis was performed after immunohistochemical evaluation of CD163 expression, a well-accepted surface marker of M2 TAMs in ESCC. To gain insight into the effect of M2 TAMs, ESCC cell lines Eca109 and KYSE150 cell...
Authors: Bayón J, Santás-Álvarez M, Ocaranza-Sánchez R, González-Juanatey C PMID: 30418158 [PubMed - as supplied by publisher]
Kits to self-test for human papillomavirus (HPV) mailed to underserved women helped to identify virtually all of those with high-risk HPV oncogenic types, in a proof-of-principle study.Medscape Medical News
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 2/22/2019 12:00:00 PM
Three female tech entrepreneurs shared their entrepreneurial journeys Monday evening, from dealing with self-doubt to running a business during breast cancer treatment. The local entrepreneurs who spoke as part of Global Entrepreneurship Week: Dr. Kim Gandy is CEO and founder of Play-it Health, which developed an adherence platform with incentives for transplant patients and those with chronic conditions. Linda Van Horn is CEO and founder of iShare Medical, wh ich provides secure, HIPAA-compliant…
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.Air date: 2/8/2019 12:00:00 PM
A rare cancer of the immune system, linked to implants, has had devastating effects on women, many of whom had reconstructive surgery after breast cancer.