Music therapy inhibits morphine-seeking behavior via GABA receptor and attenuates anxiety-like behavior induced by extinction from chronic morphine use

Conclusions Results of this study suggest that KT suppresses morphine-seeking behavior via GABA receptor pathway. In addition, KT showed to have anxiolytic effects, suggesting it has bi-directional effects on morphine.
Source: Neuroscience Letters - Category: Neuroscience Source Type: research

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Publication date: Available online 25 July 2018Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Ainsley M. Sutherland, Judith Nicholls, James Bao, Hance ClarkeAbstractThere is significant overlap in the pharmacological management of pain and psychological disorders. Appropriate treatment of patients' comorbid psychological disorders, including sleep disturbances often leads to an improvement in reported pain intensity. The three first line agents for neuropathic pain include tricyclic antidepressants and serotonin norepinephrine reuptake inhibitors which are medications originally developed ...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
You couldn’t get pregnant easily, and needed fertility treatments. You had a miscarriage. Or several. You developed complications during your pregnancy. You delivered your baby preterm. Every single one of Parijat Deshpande’s clients feels like their bodies have betrayed them because of the above reasons. Deshpande, MS, is a perinatal mind-body wellness counselor and high-risk pregnancy expert, who helps women navigate stress so they can manage pregnancy complications and give their baby a strong start to life. Psychologist Julie Bindeman, PsyD, works with women struggling with reproductive challenges, depressi...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Addiction General Grief and Loss Health-related Mental Health and Wellness Self-Help Stress Women's Issues Betrayal Fertility miscarriage Parenthood Pregnancy Source Type: blogs
Excessive cell phone use is a trend that is growing every day. We are consumed with life behind the screen. But why? Because often, in the digital world, flowers are blooming and the sun is always shining. Many of us seek and gain validation from likes and comments on photos or ideas we post online, and naturally, we crave more of that every day. But when does this craving become obsessive and possibly an addiction? Many individuals form a smartphone addiction because they can’t live without the acceptance and information they have access to on their devices. We should avoid getting trapped in the infatuation of wha...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Addiction Habits Happiness Mental Health and Wellness Self-Help Sleep Technology Phone addiction Smartphone Technology And Culture Source Type: blogs
A modern blend of yoga, Zen Buddhism, hypnosis and psychology, it ’s huge on the continent and it’s on its way hereMindfulness is the tried-and-tested tool of our times for anxiety, depression, chronic pain, addiction and more, but what if it ’s not your thing? For those too twitchy to sit still and focus on breathing, the ubiquitous mindfulness apps, self-help sheets and courses in schools and workplaces are little more than totems of uselessness. But you wouldn’t have this problem if you lived in France, Italy, Spain, Switzerland o r Portugal, because you’d be doing sophrology instead. It&rs...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Life and style Psychology Science Health & wellbeing Source Type: news
We present the case of an 80-year-old woman, single with no children, who lived alone, and, up until presentation, was able to perform activities of daily living self-sufficiently. She reported to have the support of friends and neighbors, and she lived in the small community of São Miguel Island, Azores, Portugal. She had completed two years of college before dropping out during her third year, and her last job was as an elder care-worker. She had no personal or family psychiatric antecedents and no history of alcohol or illicit drug addictions. The patient was diagnosed with DM2 two years previously and was treate...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Case Report Current Issue acute confusional state delirium diabetes hyperglycemia psychosis Source Type: research
The number of first-time prescriptions for opioid drugs has not risen since about 2010, according to UCLA researchers. However, patients taking a class of drug known to increase the risk for overdoses were likelier to receive a first-time opioid prescription — a combination that could be linked to the current surge in opioid-related deaths.People with chronic pain are often prescribed a class of medications called “benzodiazepines” to treat anxiety, panic attacks and other mental conditions that can be brought on by the stress of coping with their pain. But these people also are likelier to receive new op...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Abstract Opioid misuse, including the use of heroin and the overprescribing, misuse, and diversion of opioid pain medications, has reached epidemic proportions in the United States. As a result, there has been a dramatic increase in opioid use disorder and associated overdoses and deaths. Addiction is a chronic brain disease with a genetic component that affects motivation, inhibition, and cognition. Patient characteristics associated with successful buprenorphine maintenance treatment include stable or controlled medical or psychiatric comorbidities and a safe, substance-free environment. As a partial opioid agon...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
​Part 3 in a Four-Part Series​A 26-year-old man presented with fatigue. He complained of body aches, diarrhea, and nausea. His history was significant for chronic back pain, for which he had been prescribed oxycodone that he has taken daily for three years. He reported that he had stopped taking it two days before his visit.He denied other medication or drug use. He was alert but restless and diaphoretic. His ECG showed sinus tachycardia. His labs included a WBC of 12, Hgb of 12, glucose of 89 mg/dL, creatinine of 1.0 mg/dL, sodium of 140 mEq/L, potassium of 3.8 mEq/L, and CK of 140 U/L. He was experiencing opioid with...
Source: The Tox Cave - Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Psychosocial stress, defined here as socioenvironmental demands that tax the adaptive capacity of the individual (e.g., low socioeconomic status, childhood adversity, bullying), has repeatedly been linked to substance use disorders (SUDs). Neighborhood poverty and social support are shown to influence substance use patterns. Among smokers, multiple psychosocial stressors are associated with relapse, and acute psychosocial stress has been demonstrated to enhance cigarette craving and smoking behavior. Similarly, psychosocial stress has been associated with greater risk of relapse in individuals with alcohol and cocaine use ...
Source: Psychology of Pain - Category: Anesthesiology Source Type: blogs
There are few subjects that can stir up stronger emotions among doctors, scientists, researchers, policy makers, and the public than medical marijuana. Is it safe? Should it be legal? Decriminalized? Has its effectiveness been proven? What conditions is it useful for? Is it addictive? How do we keep it out of the hands of teenagers? Is it really the “wonder drug” that people claim it is? Is medical marijuana just a ploy to legalize marijuana in general? These are just a few of the excellent questions around this subject, questions that I am going to studiously avoid so we can focus on two specific areas: why do...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Complementary and alternative medicine Drugs and Supplements Health Pain Management Source Type: blogs
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