FDA Issues Update on Rare Breast Implant-Associated Lymphoma FDA Issues Update on Rare Breast Implant-Associated Lymphoma

As of September 30, 2017, the FDA has received a total of 414 medical device reports of anaplastic large cell lymphoma associated with breast implants, most involving implants with textured surfaces.News Alerts
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

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ConclusionsBIA-ALCL is likely to be caused by a complex interplay of factors, allowing for the variation in clinical presentation and disease progression. Our survey has already shown a growing knowledge amongst breast surgeons in the UK and Ireland as well as a switch in practice in less than a third of consultants already.Level of Evidence: not ratable
Source: European Journal of Plastic Surgery - Category: Cosmetic Surgery Source Type: research
(Natural News) A 48-year-old British woman survived a rare blood cancer that was triggered by her breast implants. Known as anaplastic large cell lymphoma (ALCL), this type of cancer is said to be a result of a reaction between the white blood cells and the new generation of rough surfaced breast implants introduced a decade...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Dave LevitanJun 6, 2018A case series of rare peripheral T-cell lymphoma that is associated with breast implants found that most cases have an indolent clinical course.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
CONCLUSION: In the literature, some articles describe correlation between connective tissue diseases and silicone breast implants, but the pathogenetic mechanisms are unknown. We report a rare case of breast morphea after positioning a silicone implant in a patient who had undergone mastectomy. This clinical report represents an interesting model of multidisciplinary management of a patient with breast cancer who developed an uncommon dermatologic disease. Further studies are needed to clarify the association between silicone implants and breast morphea. PMID: 29714655 [PubMed - as supplied by publisher]
Source: Tumori - Category: Cancer & Oncology Tags: Tumori Source Type: research
This article discusses different types of breast implants and some of the common adverse effects associated with them including contracture, rupture, leakage, and infection. The clinical and imaging appearances of these adverse effects are presented. In addition, the article describes findings and recommendations regarding rare breast implant-associated adverse effects such as anaplastic large cell lymphoma and breast fibromatosis. PMID: 29793920 [PubMed - in process]
Source: Radiologic Technology - Category: Radiology Authors: Tags: Radiol Technol Source Type: research
More than 500 women worldwide have developed a CD30+ T-cell lymphoma around breast implants, strongly suggesting a cause and effect relationship, and designated as breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). The mechanism of lymphomagenesis is unknown. Recently, a bacterial biofilm containing gram negative bacilli was discovered on the surface of breast implants associated with ALCL. We and others have described overexpression of the proto-oncogene JUNB and mutations of JAK1/2, TP53 and STAT3 in BIA-ALCL.
Source: Human Pathology - Category: Pathology Authors: Source Type: research
More than 500 women worldwide have developed a CD30+ T-cell lymphoma around breast implants, strongly suggesting a cause-and-effect relationship, and designated as breast implant –associated anaplastic large cell lymphoma (BIA-ALCL). The mechanism of lymphomagenesis is unknown. Recently, a bacterial biofilm containing gram-negative bacilli was discovered on the surface of breast implants associated with ALCL. We and others have described overexpression of the proto-oncogen e JUNB and mutations of JAK1/2, TP53 and STAT3 in BIA-ALCL.
Source: Human Pathology - Category: Pathology Authors: Tags: Original contribution Source Type: research
More than 500 women worldwide have developed a CD30+ T-cell lymphoma around breast implants, strongly suggesting a cause and effect relationship, and designated as breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). The mechanism of lymphomagenesis is unknown. Recently, a bacterial biofilm containing gram negative bacilli was discovered on the surface of breast implants associated with ALCL. We and others have described overexpression of the proto-oncogene JUNB and mutations of JAK1/2, TP53 and STAT3 in BIA-ALCL.
Source: Human Pathology - Category: Pathology Authors: Source Type: research
The U.S. Food and Drug Administration (FDA) on March 21 released an update...Read more on AuntMinnie.comRelated Reading: FDA issues update on cancer linked to breast implants Use MRI to diagnose PIP breast implant ruptures, Dutch say MRI adds to cancer detection in women with breast implants Unusual breast implant sensations while flying: Mystery solved Radiotherapy complicates implant-based breast reconstruction
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Women with breast implants have an increased risk of a type of lymphoma that can usually be cured by surgery alone — but not always.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Implants Breasts Allergan Inc Breast Cancer Non-Hodgkin's Lymphoma Mentor Worldwide LLC Food and Drug Administration American Society for Aesthetic Plastic Surgery Source Type: news
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