Ethiopia:More Concern for Kidney Disease Prevention

[Ethiopian Herald] Chronic, Non Communicable Diseases (NCDs), particularly cardiovascular, hypertension, diabetes mellitus and Chronic Kidney Diseases (CKD) have now replaced the communicable diseases and become the leading public health threat and economic cost worldwide, consuming 80 percent of many health care budgets, as sources indicate.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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This study sought to fill this knowledge gap.
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Tags: Clinical short communication Source Type: research
ConclusionPatiromer decreased serum K+ through 52 weeks in patients with hyperkalemia, chronic kidney disease, and heart failure with EF>40%, all of whom were taking RAAS inhibitors. These post-hoc results require prospective evaluation, but suggest that patiromer allows control of hyperkalemia in heart failure patients with EF>40% on RAAS inhibitors.ResultOverall, 55 out of 306 randomized patients had heart failure with EF>40% (100% Caucasian, 75% male, 69% ≥65 years of age). Mean (SD) EF was 48 (7)% and mean (SD) eGFR was 41 (13) mL/min/1.73 m² at baseline. All patients had hypertension (mean BP 155/83 m...
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
This study developed an amino acid-based metabolic panel and sought to see whether this panel could add diagnostic and prognostic value to currently used B-type natriuretic peptide (BNP) measurements. Mass spectrometry and ultra-performance liquid chromatography were performed on 1288 participants, including 129 normal controls and 712 patients at HF stages A to D in the initial cohort and 447 stage C patients in the validation cohort. Patients were followed up for composite events (death/HF-related rehospitalization). Histidine, ornithine, and phenylalanine were 3 metabolites found strongly significant to identify patient...
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
Background: Polycythemia is characterized by increased blood viscosity and a chronic inflammatory state possibly giving rise to excessive thromboembolic events and hypertensive cardiovascular disease. We aimed to study the relationship between polycythemia and cardiac risk factors using a large national registry. Methods: Patients more than 18 years with a diagnosis of polycythemia were identified from the National Inpatient Sample 2009–2010 database using International Classification of Diseases; Ninth Edition (ICD-9) code 238.4. Demographics, cardiac risk factors, and cardiovascular events were identified. Re...
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS Source Type: research
The Na/K ratio in urine stands for the dietary of sodium and potassium intake in patients with chronic kidney disease remains unclear for the renal progression. We aimed to determine the risk of progression of chronic kidney disease based on the Na/K ratio in a 24-hour urine collection. We determined the association between the progression of renal disease and 24-hour urinary sodium and potassium (Na/K) ratios in 2238 patients over a 5-year timespan using data obtained from the KoreaN cohort study for Outcomes in patients With Chronic Kidney Disease (KNOW-CKD). Renal events were defined as a 50% decrease in the glomerular...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
In conclusion, management of blood pressure both at office and home was found to be important for the reno-protective effects of sodium-glucose cotransporter 2 inhibitors along with strict blood pressure management. PMID: 30373408 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Hypertension - Category: Cardiology Authors: Tags: Clin Exp Hypertens Source Type: research
Publication date: November–December 2018Source: The Journal of Foot and Ankle Surgery, Volume 57, Issue 6Author(s): Ahmet Erdoğan, Arife Polat Düzgün, Kubra Erdoğan, Murat Bulut Özkan, Faruk CoşkunAbstractDiabetic foot ulcer is a common chronic complication of diabetes mellitus. In addition to conventional primary therapy, there are adjuvant therapy methods such as hyperbaric oxygen therapy for the healing of diabetic foot ulcer wounds. The present study aimed to determine the efficacy of hyperbaric oxygen therapy in diabetic foot ulcers based on Wagner classification. It was performed retrospective...
Source: The Journal of Foot and Ankle Surgery - Category: Orthopaedics Source Type: research
Chronic kidney disease (CKD) is recognised as a global public health problem, more prevalent in older persons and associated with multiple co-morbidities. Diabetes mellitus and hypertension are common aetiolog...
Source: Journal of Translational Medicine - Category: Research Authors: Tags: Review Source Type: research
Abstract Type 2 diabetes mellitus (T2DM) substantially increases the risk of cardiovascular events, including heart failure (HF), due to complications such as hypertension, obesity and dyslipidemia based on metabolic syndrome, which plays the central pathological role in HF. A reason is that T2DM causes left ventricular (LV) diastolic dysfunction beginning in the early phase of the disease, which in turn increases the risk of development of HF independently of the control of blood glucose levels, blood pressure or the presence of coronary artery diseases. Intracellular metabolic disorders and increased oxidative s...
Source: Clin Med Res - Category: Research Authors: Tags: J Clin Med Res Source Type: research
A 77-year-old male with a history of hypertension, chronic kidney disease, and poorly-controlled type 2 diabetes mellitus presented to our intensive care unit from an outside hospital with complicated necrotizing otitis externa. One month prior, the patient developed purulent drainage from the right external auditory canal with associated hearing loss. One week prior, he was prescribed ciprofloxacin/dexamethasone otic suspension and oral ciprofloxacin tablets for his symptoms. Despite this regimen, he experienced progressive purulent otorrhea, along with subjective fevers, chills, headaches, and altered mental status.
Source: The American Journal of Medicine - Category: General Medicine Authors: Source Type: research
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