Bee Venom Acupuncture: A Therapy That Could Kill You
Researchers report the recent case of a 55-year-old Spanish woman who died after having an alternative procedure known as bee venom acupuncture, in which live bee stings were used, as opposed to standard acupuncture needles.
Preclinical models indicate that DNA damage induces type I interferon (IFN), which is crucial for the induction of an anti-tumor immune response. In human cancers, however, the association between DNA damage and an immunogenic cell death (ICD), including the release and sensing of danger signals, the subsequent ER stress response and a functional IFN system, is less clear.Methods: Neoadjuvant-treated colorectal liver metastases (CLM) patients, undergoing liver resection in with a curative intent, were retrospectively enrolled in this study (n=33). DNA damage (γH2AX), RNA and DNA sensors (RIG-I, DDX41, cGAS, STING), E...
Conclusion: Our findings suggest that Ly6C+ monocytes and mtDNA-induced Ly6C+ monocyte PGE2 production may be part of a feedback mechanism that contributes to the resolution of cationic nanocarrier-induced inflammatory toxicity and may have important implications for understanding nanoparticle biocompatibility and designing better, safer drug delivery systems.
A radiologist from Beverly Hills, CA, was sentenced to 10 years in prison after...Read more on AuntMinnie.comRelated Reading: Beverly Hills radiologist convicted in kickback scheme Radiologist nabbed in Calif. workers' comp fraud sting Imaging firm pays $647K to settle fraud charges
Publication date: 19 June 2018 Source:Cell Reports, Volume 23, Issue 12 Author(s): Marina Martin, Aoi Hiroyasu, R. Marena Guzman, Steven A. Roberts, Alan G. Goodman The vertebrate protein STING, an intracellular sensor of cyclic dinucleotides, is critical to the innate immune response and the induction of type I interferon during pathogenic infection. Here, we show that a STING ortholog (dmSTING) exists in Drosophila, which, similar to vertebrate STING, associates with cyclic dinucleotides to initiate an innate immune response. Following infection with Listeria monocytogenes, dmSTING activates an innate immune response vi...
The best way to treat a jellyfish sting is to: rinse the area with vinegar, remove visible tentacles and soak the skin in hot water.
Wen-Yu Cheng, Xiao-Bing He, Huai-Jie Jia, Guo-Hua Chen, Qi-Wang Jin, Zhao-Lin Long, Zhi-Zhong Jing
Updated Date: Jun 14, 2018 EST
Jellyfish have a mighty sting as hundreds of beachgoers in Florida have discovered. More than 800 people were reported to have been stung recently at Central Florida beaches.?Dr. Michael Boniface, an emergency department physician with Mayo Clinic, says?most jellyfish that beachgoers encounter in the U.S. contiguous lower 48 states can cause symptomatic and problematic skin [...]
Along the Central Florida coast, a spike in moon jellyfish stings have kicked off summer in a painful way.
ConclusionsSPT300 shows a high but not substantially superior sensitivity utilizing both WV and BV extract for diagnosis of HV allergy compared to SPT100 and IDT1. However, since SPT300 with BV extract demonstrated a very low specificity, our results indicate that SPT300 has limited added value in the diagnosis of HV alle rgy.