Bee Venom Acupuncture: A Therapy That Could Kill You

Researchers report the recent case of a 55-year-old Spanish woman who died after having an alternative procedure known as bee venom acupuncture, in which live bee stings were used, as opposed to standard acupuncture needles.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news

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(MedPage Today) -- A 34-year-old woman went to urgent care while on a camping trip. She was setting up a tent when she was stung by some type of insect on her finger. Before she could untangle herself from the cloth, she had been stung several more times on her hand and arm, still never seeing the culprit. A short time later she began vomiting and noticed her stings were erythematous. Can you diagnose the patient?
Source: MedPage Today Dermatology - Category: Dermatology Source Type: news
Parents and healthcare providers are reported to be “desperate” for solutions for dealing with temper tantrums and other extreme “disruptive behaviors.” Reports state that at least 10,000 and as many as 20,000 infants under the age of two in 2014 were prescribed drugs such as risperidone, quetiapine, and other antipsychotic medications, sugge sting that parents may have lost faith in their inner abilities to create an environment for their infant. Dr. Maria Montessori, concluded from her work that the nervous troubles of many “difficult” children can be traced to one of the most “h...
Source: Archives of Psychiatric Nursing - Category: Nursing Authors: Source Type: research
Abstract Stinging accidents involving wasp venom are a notable cause of acute kidney injury (AKI) in Asia. However, very little attention has been paid to the understanding of the mechanisms involved in this type of AKI. The aims of this review are to explore the evidence for the mechanisms and the therapeutic role of renal replacement therapy of wasp venom and AKI. A systematic literature search was conducted using PubMed for the association among wasp venom and AKI. Wasp venom is a complex mixture of biologically active components, including enzymes, amines, and peptides. Wasp venom may induce local anaphylaxis ...
Source: Toxicon - Category: Toxicology Authors: Tags: Toxicon Source Type: research
We describe five divers presenting with suspected decompression sickness, where the probable diagnosis was jellyfish envenoming. PMID: 30856668 [PubMed - in process]
Source: Diving and Hyperbaric Medicine - Category: Sports Medicine Tags: Diving Hyperb Med Source Type: research
​BY RYAN LYNCH, MD, &MARK SUPINO, MDA 2-year-old girl was playing outside when she spotted a furry caterpillar. Like her stuffed animals, it was fluffy and had long hair. She let the insect crawl on her legs, but then suddenly screamed in pain. Her parents brought her to the ED, though she was no longer in distress by the time she arrived.The patient had a large urticarial lesion on her inner right thigh and a smaller one on her left thigh. (Photo.) There were no puncture wounds, bite marks, or barbs visible or palpable. Her vital signs and physical exam were within normal limits. The patient's father had captured th...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
AbstractSTING is a newly identified adaptor protein for sensing cytosolic nucleic acid. It is well established that STING plays a crucial role in innate immune response via inducing production of type I IFN. Emerging evidence suggests that the activation of STING-dependent signaling is also implicated in the process of cell death, such as apoptosis, pyroptosis, necroptosis, and autophagy. Of note, the pro-death outcome is even predominant in certain cell types, like lymphocytes, myeloid cells, and hepatocytes. Given that STING agonists are being tested for enhancing antitumor immune responses, it is necessary to fully unde...
Source: Immunologic Research - Category: Allergy & Immunology Source Type: research
Abstract The mammalian innate immune system serves as the front line of the host to eliminate invading pathogens. The receptors that sense invading pathogens or the pathogen-associated molecules localized at various membrane compartments that include the plasma membrane, endosomes, and the endoplasmic reticulum. Intriguingly, growing evidence indicates that the sites of pathogen detection do not always represent the site where innate immune signal is triggered. Rather, pathogen detection often induces translocation of the receptors by membrane trafficking. Furthermore, dysregulated membrane trafficking of the rece...
Source: Current Opinion in Cell Biology - Category: Cytology Authors: Tags: Curr Opin Cell Biol Source Type: research
Publication date: Available online 9 March 2019Source: Journal of Microbiological MethodsAuthor(s): Reinhard Sting, Tobias Eisenberg, Maja HrubenjaAbstractAnalyses of short subunit gene sequences have been established for taxonomic classification and identification of bacteria and fungi. To produce partial bacterial ribosomal 16S rRNA and rpoB and fungal ribosomal ITS/LSU gene sequences for DNA sequencing, real-time PCR assays supplemented with the nucleic acid stain SYBR Green were created. Generation of PCR products was monitored based on amplification and melting curves. The PCR products were subsequently subjected to S...
Source: Journal of Microbiological Methods - Category: Microbiology Source Type: research
Abstract Oncology immunotherapy has gained significant advances in recent years and benefits cancer patients with superior efficacy and superior clinical responses. Currently over ten immune checkpoint antibodies targeting CTLA-4 and PD-1/PD-L1 have received regulatory approval worldwide and over thousands are under active clinical trials. However, compared to the rapid advance of monoclonal antibody (mAb), studies on immunotherapeutic small molecules have far lagged behind. Small molecule immunotherapy not only can target immunosuppressive mechanisms similar to mAbs, but also can stimulate intracellular pathways ...
Source: Current Topics in Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Top Med Chem Source Type: research
DNA is highly immunogenic. It represents a key pathogen-associated molecular pattern (PAMP) during infection. Host DNA can, however, also act as a danger-associated molecular pattern (DAMP) and elicit strong inflammatory responses. The cGAS-STING pathway has emerged as a major pathway that detects intracellular DNA. Here, we highlight recent advances on how cGAS and STING mediate inflammatory responses and how these are regulated, allowing cells to readily respond to infections and noxious agents while avoiding the inappropriate sensing of self-DNA. A particular focus is placed on the role of cGAS in the context of sterile...
Source: ScienceNOW - Category: Science Authors: Tags: Immunology, Online Only review Source Type: news
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