Early urinary markers for diabetic and other kidney diseases.

CONCLUSION: Although significant advances have been made in medical therapy, the degree of morbidity and mortality associated with kidney diseases remain despondently high. Besides the serum markers, urinary markers may provide a better prediction of progression of the damage to the kidneys in diabetic patients. PMID: 29552988 [PubMed - as supplied by publisher]
Source: Current Drug Targets - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Targets Source Type: research

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Rev Diabet Stud. 2021 Spring;17(1):1-10. doi: 10.1900/RDS.2021.17.1. Epub 2021 May 10.ABSTRACTUncontrolled or chronic hyperglycemia causes kidney failure induced by the dysfunction of biomolecules and upregulation of inflammatory cytokines and growth factors. The renin-angiotensin system (RAS) is incorporated in the regulation of renal hemodynamics. In a healthy state, local RAS is independent of systemic RAS. However, in pathological conditions such as chronic hyperglycemia, angiotensin II (Ang II) increases locally and causes tissue damage, mainly through the induction of oxidative stress, inflammation, and upregulation ...
Source: Review of Diabetic Studies - Category: Endocrinology Authors: Source Type: research
Acta Clin Croat. 2020 Dec;59(4):661-666. doi: 10.20471/acc.2020.59.04.12.ABSTRACTThe aim of this study was to evaluate complete blood cell count parameters including red blood cell indices, white blood cell subtypes, and platelet indices for predicting deep vein thrombosis (DVT). A total of 71 (44 male and 27 female) patients with acute femoral and popliteal DVT diagnosed by doppler ultrasonography during a period of seven years (2011-2017) were included in the study. By matching age and gender, 142 (88 male and 54 female) subjects diagnosed with venous insufficiency in the same time interval were assigned as control group...
Source: Acta Clinica Croatica - Category: General Medicine Authors: Source Type: research
Rev Diabet Stud. 2021 Spring;17(1):1-10. doi: 10.1900/RDS.2021.17.1. Epub 2021 May 10.ABSTRACTUncontrolled or chronic hyperglycemia causes kidney failure induced by the dysfunction of biomolecules and upregulation of inflammatory cytokines and growth factors. The renin-angiotensin system (RAS) is incorporated in the regulation of renal hemodynamics. In a healthy state, local RAS is independent of systemic RAS. However, in pathological conditions such as chronic hyperglycemia, angiotensin II (Ang II) increases locally and causes tissue damage, mainly through the induction of oxidative stress, inflammation, and upregulation ...
Source: Review of Diabetic Studies - Category: Endocrinology Authors: Source Type: research
Acta Clin Croat. 2020 Dec;59(4):661-666. doi: 10.20471/acc.2020.59.04.12.ABSTRACTThe aim of this study was to evaluate complete blood cell count parameters including red blood cell indices, white blood cell subtypes, and platelet indices for predicting deep vein thrombosis (DVT). A total of 71 (44 male and 27 female) patients with acute femoral and popliteal DVT diagnosed by doppler ultrasonography during a period of seven years (2011-2017) were included in the study. By matching age and gender, 142 (88 male and 54 female) subjects diagnosed with venous insufficiency in the same time interval were assigned as control group...
Source: Acta Clinica Croatica - Category: General Medicine Authors: Source Type: research
Acta Clin Croat. 2020 Dec;59(4):661-666. doi: 10.20471/acc.2020.59.04.12.ABSTRACTThe aim of this study was to evaluate complete blood cell count parameters including red blood cell indices, white blood cell subtypes, and platelet indices for predicting deep vein thrombosis (DVT). A total of 71 (44 male and 27 female) patients with acute femoral and popliteal DVT diagnosed by doppler ultrasonography during a period of seven years (2011-2017) were included in the study. By matching age and gender, 142 (88 male and 54 female) subjects diagnosed with venous insufficiency in the same time interval were assigned as control group...
Source: Acta Clinica Croatica - Category: General Medicine Authors: Source Type: research
Acta Clin Croat. 2020 Dec;59(4):661-666. doi: 10.20471/acc.2020.59.04.12.ABSTRACTThe aim of this study was to evaluate complete blood cell count parameters including red blood cell indices, white blood cell subtypes, and platelet indices for predicting deep vein thrombosis (DVT). A total of 71 (44 male and 27 female) patients with acute femoral and popliteal DVT diagnosed by doppler ultrasonography during a period of seven years (2011-2017) were included in the study. By matching age and gender, 142 (88 male and 54 female) subjects diagnosed with venous insufficiency in the same time interval were assigned as control group...
Source: Acta Clinica Croatica - Category: General Medicine Authors: Source Type: research
Rev Diabet Stud. 2021 Spring;17(1):1-10. doi: 10.1900/RDS.2021.17.1. Epub 2021 May 10.ABSTRACTUncontrolled or chronic hyperglycemia causes kidney failure induced by the dysfunction of biomolecules and upregulation of inflammatory cytokines and growth factors. The renin-angiotensin system (RAS) is incorporated in the regulation of renal hemodynamics. In a healthy state, local RAS is independent of systemic RAS. However, in pathological conditions such as chronic hyperglycemia, angiotensin II (Ang II) increases locally and causes tissue damage, mainly through the induction of oxidative stress, inflammation, and upregulation ...
Source: Review of Diabetic Studies - Category: Endocrinology Authors: Source Type: research
Acta Clin Croat. 2020 Dec;59(4):661-666. doi: 10.20471/acc.2020.59.04.12.ABSTRACTThe aim of this study was to evaluate complete blood cell count parameters including red blood cell indices, white blood cell subtypes, and platelet indices for predicting deep vein thrombosis (DVT). A total of 71 (44 male and 27 female) patients with acute femoral and popliteal DVT diagnosed by doppler ultrasonography during a period of seven years (2011-2017) were included in the study. By matching age and gender, 142 (88 male and 54 female) subjects diagnosed with venous insufficiency in the same time interval were assigned as control group...
Source: Acta Clinica Croatica - Category: General Medicine Authors: Source Type: research
Acta Clin Croat. 2020 Dec;59(4):661-666. doi: 10.20471/acc.2020.59.04.12.ABSTRACTThe aim of this study was to evaluate complete blood cell count parameters including red blood cell indices, white blood cell subtypes, and platelet indices for predicting deep vein thrombosis (DVT). A total of 71 (44 male and 27 female) patients with acute femoral and popliteal DVT diagnosed by doppler ultrasonography during a period of seven years (2011-2017) were included in the study. By matching age and gender, 142 (88 male and 54 female) subjects diagnosed with venous insufficiency in the same time interval were assigned as control group...
Source: Acta Clinica Croatica - Category: General Medicine Authors: Source Type: research
Rev Diabet Stud. 2021 Spring;17(1):1-10. doi: 10.1900/RDS.2021.17.1. Epub 2021 May 10.ABSTRACTUncontrolled or chronic hyperglycemia causes kidney failure induced by the dysfunction of biomolecules and upregulation of inflammatory cytokines and growth factors. The renin-angiotensin system (RAS) is incorporated in the regulation of renal hemodynamics. In a healthy state, local RAS is independent of systemic RAS. However, in pathological conditions such as chronic hyperglycemia, angiotensin II (Ang II) increases locally and causes tissue damage, mainly through the induction of oxidative stress, inflammation, and upregulation ...
Source: Review of Diabetic Studies - Category: Endocrinology Authors: Source Type: research
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