Chiral Organic Base Catalyst with Halogen Bonding Donor Functionality: Asymmetric Mannich Reaction of Malononitrile with N-Boc Aldimines and Ketimines

Chem. Commun., 2018, Accepted Manuscript DOI: 10.1039/C8CC00865E, CommunicationSatoru Kuwano, Takumi Suzuki, Yusei Hosaka, Takayoshi Arai Chiral organic base catalyst with halogen-bonding-donor functionality was developed through a simple condensation reaction between cinchona alkaloid-derived chiral diamine and 2,3,4,5-tetrafluoro-6-iodobenzoic acid. The quinidine-derived acid/base catalyst smoothly promoted asymmetric Mannich... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Chem. Commun. latest articles - March 21, 2018 Category: Chemistry Authors: Satoru Kuwano Source Type: research