[ASAP] Discovery of [ < italic toggle="yes" > cis < /italic > -3-({(5 < italic toggle="yes" > R < /italic > )-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1 < italic toggle="yes" > H < /italic > -inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5 < italic toggle="yes" > H < /italic > )-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor ?t Inverse Agonist

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.8b00061

Source: Journal of Medicinal Chemistry - March 14, 2018 Category: Chemistry Authors: Mitsunori Kono, Atsuko Ochida, Tsuneo Oda, Takashi Imada, Yoshihiro Banno, Naohiro Taya, Shinichi Masada, Tetsuji Kawamoto, Kazuko Yonemori, Yoshi Nara, Yoshiyuki Fukase, Tomoya Yukawa, Hidekazu Tokuhara, Robert Skene, Bi-Ching Sang, Isaac D. Hoffman, Gyo Source Type: research