Imaging Parkinsonian Pathology in Substantia Nigra with MRI

This article outlines iron-sensitive and diffusion-sensitive MRI contrasts, and provides an overview of neuromelanin-sensitive MRI techniques. The application of these techniques to image parkinsonian pathobiology in substantia nigra is then reviewed, with a focus on neuromelanin-sensitive imaging methods for the accurate and reproducible study of PD-related changes in SNc. These advances may help resolve current controversies surrounding MRI investigations of substantia nigra in PD and related disorders.

http://link.springer.com/10.1007/s40134-018-0272-x

Source: Current Radiology Reports - March 20, 2018 Category: Radiology Source Type: research