anaphylaxis triggered by radiocontrast media and local anesthetics; what should be done when they are essential?

[ANAPHYLAXIS TRIGGERED BY RADIOCONTRAST MEDIA AND LOCAL ANESTHETICS; WHAT SHOULD BE DONE WHEN THEY ARE ESSENTIAL?] Arerugi. 2018;67(2):98-101 Authors: Yamaguchi M PMID: 29553120 [PubMed - in process]
Source: Allergology International - Category: Allergy & Immunology Tags: Arerugi Source Type: research

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ConclusionNo patient experienced adverse events directly related to gadoterate meglumine. Only two adverse events were reported to have occurred in the initial 2  h after the exam, while the rest were reported on the 24-h follow-up call. The higher reported rate of adverse events in this study may be related to concomitant sedation/anesthesia as well as to overreporting from parents on the 24-h follow-up questionnaire. The study confirms a good safety profi le for gadoterate meglumine in this very sensitive population.
Source: Pediatric Radiology - Category: Radiology Source Type: research
AbstractPurpose of the reviewThe γ-cyclodextrin sugammadex, chemically modified to encapsulate the steroidal muscle relaxant rocuronium, was introduced into anesthesia as the first selective relaxant binding agent to reverse neuromuscular blockade. In the face of sugammadex’s alleged propensity to cause anaphylaxis, the agent wa s finally approved by the FDA in 2015. With its steadily increasing usage, it has become apparent that there is a small but concerning incidence of perioperative anaphylaxis to sugammadex and some reactions that are anaphylactic like but where diagnosis has not been definitive. The purp...
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research
Abstract Atrial fibrillation is the most common cardiac arrhythmia in western society affecting more than 35 million individuals worldwide annually. It is a common postoperative complication and may also occur spontaneously during general and local anesthesia administration. Aging, diabetes mellitus, hypertension, and cardiovascular diseases including cardiomyopathies, congenital cardiac anomalies, heart failure, myocardial ischemia, pericarditis, previous cardiac surgery, vascular disease, and valvular heart disease are some correlated factors. Beyond age, increased incidence of atrial fibrillation has been corre...
Source: Annals of Cardiac Anaesthesia - Category: Anesthesiology Authors: Tags: Ann Card Anaesth Source Type: research
CONCLUSIONS: This secondary analysis demonstrates that the incidence of severe critical incidence was lower in Italy in comparison to that reported for Europe. This low rate of critical events may be related to the high expertise and experience of the anesthesiologists in charge of the children in the Italian centres that participated to APRICOT. PMID: 31820874 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
CONCLUSION: Proper workup after an intraoperative anaphylactic event has a fairly good chance of identifying the causative allergen. These results are useful for patient management and the planning of subsequent anaesthetic procedures. PMID: 31788702 [PubMed - as supplied by publisher]
Source: Singapore Medical Journal - Category: General Medicine Authors: Tags: Singapore Med J Source Type: research
Abstract We here report that a 71-year-old Japanese woman with a history of anaphylaxis induced by muscle relaxants had local anesthetic systemic toxicity (LAST) following an abdominal surgery under general anesthesia with combined spinal-epidural anesthesia without muscle relaxants. The total dosages of local anesthetics reached 0.67 mg/kg of ropivacaine and 11.5 mg/kg of lidocaine over 12.5 h to obtain sufficient muscle relaxation for surgery. Regional anesthesia is useful in cases in which muscle relaxants are to be avoided during a surgery. However, especially for a patient with risk factors and prolonged surg...
Source: Acta Med Okayama - Category: Universities & Medical Training Authors: Tags: Acta Med Okayama Source Type: research
Publication date: Available online 29 November 2019Source: Anaesthesia &Intensive Care MedicineAuthor(s): Nina Hjelde, Abdul G. LalkhenAbstractAnaphylaxis is defined as a ‘severe life-threatening generalized or systemic hypersensitivity reaction’. Anaphylactic shock is characterized by generalized vasodilation and increased capillary permeability, leading to reduction in cardiac output. The pathophysiology of anaphylaxis can be described as immunologic and non-immunologic. The National Audit Project 6 (NAP 6) has recently investigated perioperative anaphylaxis and this article will outline some key updates ...
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
The rate of caesarean delivery (CD) has tripled in the last three decades.1 Most CD are performed under regional anaesthesia because of its various advantages: better parental experience associated with the delivery; avoidance of exposure to general anaesthetic agents that have a risk of causing anaphylaxis and uterine atony; avoidance of intraoperative awareness; and reduced mortality.2 Importantly, regional anaesthesia avoids or minimizes the risks of airway management and its associated complications such as failed intubation, oesophageal intubation and aspiration.
Source: International Journal of Obstetric Anesthesia - Category: Anesthesiology Authors: Tags: Review article Source Type: research
Neuromuscular blocking agents (NMBA) such as rocuronium, vecuronium, cisatracurium, succinylcholine, etc. are commonly used during anesthesia induction. There are reported cases of perioperative anaphylaxis due to NMBA; however, the cross reactivity between these medications is not well determined.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
Authors: Hong S, Lee J PMID: 31636240 [PubMed - as supplied by publisher]
Source: Korean Journal of Anesthesiology - Category: Anesthesiology Tags: Korean J Anesthesiol Source Type: research
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