Accurate control of dual-receptor-engineered T cell activity through a bifunctional anti-angiogenic peptide

Chimeric antigen receptors (CARs) presented on T cell surfaces enable redirection of T cell specificity, which has enormous promise in antitumor therapy. However, excessive activity and poor control over such ...

Source: Journal of Hematology and Oncology - March 20, 2018 Category: Hematology Authors: Erhao Zhang, Jieyi Gu, Jianpeng Xue, Chenyu Lin, Chen Liu, Mengwei Li, Jingchao Hao, Sarra Setrerrahmane, Xiaowei Chi, Weiyan Qi, Jialiang Hu and Hanmei Xu Tags: Research Source Type: research