Men with low sperm counts are at increased risk of illnesses

Men who have low sperm counts are at a 20 percent greater risk of developing illnesses like diabetes and heart disease, according to an Italian study linking infertility to metabolic syndrome symptoms.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Publication date: 18 October 2018Source: Cell, Volume 175, Issue 3Author(s): Vishal Singh, Beng San Yeoh, Benoit Chassaing, Xia Xiao, Piu Saha, Rodrigo Aguilera Olvera, John D. Lapek, Limin Zhang, Wei-Bei Wang, Sijie Hao, Michael D. Flythe, David J. Gonzalez, Patrice D. Cani, Jose R. Conejo-Garcia, Na Xiong, Mary J. Kennett, Bina Joe, Andrew D. Patterson, Andrew T. Gewirtz, Matam Vijay-KumarSummaryDietary soluble fibers are fermented by gut bacteria into short-chain fatty acids (SCFA), which are considered broadly health-promoting. Accordingly, consumption of such fibers ameliorates metabolic syndrome. However, incorporati...
Source: Cell - Category: Cytology Source Type: research
Authors: Moreno JA, Gomez-Guerrero C, Mas S, Sanz AB, Lorenzo O, Ruiz-Ortega M, Opazo L, Mezzano S, Egido J Abstract INTRODUCTION: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease (CKD) and end stage renal disease (ESRD). Beyond the new anti-diabetic drugs that possess markedly cardiovascular and renal protective effects, no novel direct therapies for DN have become available on the market in the last twenty years. Recently well-designed clinical trials for the treatment of DN, with attractive pathogenetic rationale, e.g. bardoxolone and atrasentan, were cancelled or stopped because of safet...
Source: Expert Opinion on Investigational Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research
Objectives: To evaluate all patients who received gentamicin for open fracture treatment and determine the incidence of, and risk factors for, kidney injury in this population. Design: Retrospective, case control. Setting: Single institution; Level 1 trauma center. Patients/Participants: A retrospective chart review identified patients who received gentamicin for open fracture antibiotic treatment from January 2008 to December 2012. Overall, 371 patients met the inclusion criteria and were categorized into 2 groups using risk, injury, failure, loss of kidney function, and end-stage kidney disease criteria: norma...
Source: Journal of Orthopaedic Trauma - Category: Orthopaedics Tags: Original Article Source Type: research
Conclusions: NVI following KD is more common after lower energy-level mechanisms. Obesity is associated with NVI in lower energy-level mechanisms. Physicians should be vigilant in screening for NVI in the setting of KD even with seemingly benign mechanisms of injury, especially in patients with obesity. Level of Evidence: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Source: Journal of Orthopaedic Trauma - Category: Orthopaedics Tags: Original Article Source Type: research
Authors: Koda R, Tsuchida M, Iino N, Narita I Abstract A 68-year-old man with type 2 diabetes mellitus and chronic hepatitis B infection was referred to the nephrology department before planned surgery for hepatocellular carcinoma. He had been receiving low-dose adefovir dipivoxil (ADV) for 11 years. Laboratory findings revealed impaired re-absorption in the proximal renal tubules. He had been diagnosed with diabetic kidney disease and osteomalacia due to vitamin D deficiency; thus, ADV was not discontinued until he was referred to us. In this case, concomitant diabetes mellitus and vitamin D deficiency might have ...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Authors: Hironaka JY, Kitahama S, Sato H, Inoue M, Takahashi T, Tamori Y Abstract The effects of bariatric/metabolic surgery on glycemic control in obese type 1 diabetic patients are controversial. We herein report a case of a morbidly obese 35-year-old woman who completely recovered from slowly progressive type 1 diabetes (SPIDDM) following laparoscopic sleeve gastrectomy. Preoperatively, her body mass index (BMI) was 49.8 kg/m2 and hemoglobin A1c was 5.7% with intensive insulin therapy. Six months after bariatric/metabolic surgery, her BMI decreased to 33.2 kg/m2 and her glycemic control was normal despite the di...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
D. Possee Linda A. King Pancreatic islet transplantation is a promising treatment for type 1 diabetes mellitus offering improved glycaemic control by restoring insulin production. Improved human pancreatic islet isolation has led to higher islet transplantation success. However, as many as 50% of islets are lost after transplantation due to immune responses and cellular injury, gene therapy presents a novel strategy to protect pancreatic islets for improved survival post-transplantation. To date, most of the vectors used in clinical trials and gene therapy studies have been derived from mammalian viruses such as ade...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Hepatology,Volume 0, Issue ja, -Not available-.
Source: Hepatology - Category: Internal Medicine Authors: Source Type: research
Publication date: Available online 18 October 2018Source: Life SciencesAuthor(s): Pratibha Chauhan, Akhilesh Kumar Tamrakar, Sunil Mahajan, G.B.K.S. PrasadAbstractAimThe present study was undertaken to develop a Curcumin nanoparticle system with chitosan as a hydrophilic carrier. In addition, the anti-diabetic potential of curcumin loaded chitosan nanoparticles were assessed in comparison to those of free curcumin by examining the anti-hyperglycemic efficacy using in vitro assays.MethodsCurcumin loaded chitosan nanoparticles were prepared and characterized for particle size by transmission electron microscopy, FT-IR, diffe...
Source: Life Sciences - Category: Biology Source Type: research
This question comes up with some regularity: Is the Wheat Belly lifestyle like the Atkins’ diet? Is Wheat Belly just another name for a low-carb diet? There are indeed some important areas of overlap. The Wheat Belly lifestyle, for instance, adheres to the concept that carbohydrates, not fats, are responsible for destructive health effects and weight gain. We also need to give Dr. Robert Atkins and his low-carb predecessors great credit for voicing their opinions during an age when low-carb was an heretical, against-the-mainstream concept, given the antics of Dr. Ancel Keys, Dr. Henry Blackburn, the US Department of ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Lifestyle atkins blood sugar diabetes gluten grains Inflammation low-carb low-fat Weight Loss Source Type: blogs
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