Acupuncture found to help normalize uric acid levels, reduce risk of gout and kidney damage
(Natural News) Acupuncture helps normalize uric acid levels, reducing the risk of gout and kidney damage, according to a study published in the Journal of Traditional Chinese Medicine. Carried out by a team of researchers from Beijing University of Chinese Medicine, the study investigated the effects of acupuncture therapy at specific areas on serum uric...
No abstract available
This study was undertaken to evaluate whether NLRP3 gene transcript variants are involved in the occurrence of PG. A total of 44 acute phase PG (APPG), 52 non-acute phase PG (NAPPG) male patients, and 30 male health control (HC) were involved in this study. We measured NLRP3 and its transcript variants 2, 3, 4, 5, and 1 + 6 expressions in the PBMCs, together with the level of IL-1β in the serum. Further, PBMCs of HC were stimulated with MSU crystals. The levels of NLRP3, NLRP3 gene transcript variants 2, 3, 4 mRNA, and protein expressions were significantly lower in the APPG and NAPPG groups than in the...
Abstract Uric acid (UA) is a metabolite of purine degradation and is involved in gout flairs and kidney stones formation. GLUT9 (SLC2A9) was previously shown to be a urate transporter in vitro. In vivo, humans carrying GLUT9 loss-of-function mutations have familial renal hypouricemia type 2, a condition characterized by hypouricemia, UA renal wasting associated with kidney stones, and an increased propensity to acute renal failure during strenuous exercise. Mice carrying a deletion of GLUT9 in the whole body are hyperuricemic and display a severe nephropathy due to intratubular uric acid precipitation. However, th...
PMID: 30082538 [PubMed - in process]
Conditions: Gout Flare; Gout Attack Interventions: Dietary Supplement: Tart cherry juice; Other: Fruit-flavoured placebo drink Sponsors: Sheffield Hallam University; Cherry Research Committee Not yet recruiting
(MedPage Today) -- Effective even with renal impairment
At one point, Zurampic, an experimental gout drug, had been touted as a blockbuster-in-the-making.