In major affective disorders, early life trauma predict increased nitro-oxidative stress, lipid peroxidation and protein oxidation and recurrence of major affective disorders, suicidal behaviors and a lowered quality of life - Moraes JB, Maes M, Roomruangwong C, Bonifacio KL, Barbosa DS, Vargas HO, Anderson G, Kubera M, Carvalho AF, Nunes SOV.

Early life trauma (ELT) may increase the risk towards bipolar disorder (BD) and major depression (MDD), disorders associated with activated neuro-oxidative and neuro-nitrosative stress (O&NS) pathways. It has remained elusive whether ELTs are associated wi...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

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The objective of this study was to explore suicidal behavio...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
BACKGROUND: Suicide is one of the leading causes of death in bipolar disorder (BD); violent suicide attempts are associated with the highest level of lethality. We aimed to evaluate factors related to the risk of violent suicide in a large naturalistic sam...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
Publication date: Available online 18 November 2019Source: Journal of Psychiatric ResearchAuthor(s): Sophia C. Gaynor, Eric T. Monson, Marie E. Gaine, Michael S. Chimenti, Rachel D. Reichman, Meredith Parsons, Lalita Oonthonpan, Peter P. Zandi, James B. Potash, Virginia L. WillourAbstractWe previously conducted a genome-wide association study (GWAS) of attempted suicide within bipolar disorder, which implicated common variation in the 2p25 region primarily in males. The top association signal from our GWAS occurred in an intergenic region of 2p25 (p = 5.07 × 10−8) and was supported by two independent st...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Individuals with childhood or adolescent onset bipolar disorder (BD) have a more difficult course and outcome than individuals with adult onsets (Faedda et al., 1995; Post et al., 2017). Studies have shown that an earlier age of onset is associated wit...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
BACKGROUND: Increasing evidence suggests Bipolar Disorder (BD) to be frequently associated to a history of traumatic experiences and Post-traumatic Stress Disorder (PTSD), with consequent greater symptoms severity, number of hospitalizations and worsening ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
 Have you ever wondered what it’s like to be an inpatient in a psych ward? In this two-part series, we go into detail about Gabe’s inpatient stay starting with the events that lead him to be an inpatient, and what his days were like after he was admitted. We talk about common misconceptions that you may have around what happens while you’re admitted, what your day looks like and who you’d spend time with. (Transcript Available Below) SUBSCRIBE &REVIEW About The Not Crazy Podcast Hosts Gabe Howard is an award-winning writer and speaker who lives with bipolar disorder. He is the author of t...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Bipolar Depression General Not Crazy Podcast Psychiatry Psychotherapy Suicide Treatment Source Type: blogs
BACKGROUND: Suicide is a public health crisis, accounting for more than 47,000 deaths in the United States annually. Individuals with Bipolar Disorder (BD) are at a disproportionately greater risk of suicidal behaviors. Prior studies indicate the significa...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Authors: Sher L PMID: 31726423 [PubMed - as supplied by publisher]
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
Say the word. Suicide. Say it aloud. Say it more than once. Say it until it sounds like any other word.  Our minds give words power, connotations, and destructive or healing qualities. Words, alone, can attack the body with symptoms of fear and uncertainty and, at the same time, be inexact and open to interpretation. What if you could rob a word like “suicide” of some of its isolating effect and control?  Words are serious business. What they represent – true or not – are real problems that need real solutions. Taking control of the power of words is one strategy that places the focus wher...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Communication Stigma Suicide crisis Power of words Semantics Source Type: blogs
The phrase “sacred masculine” can evoke images of patriarchal religiosity.  But it has a different meaning for today’s guest. For Miguel Dean, the sacred masculine is an ideal, embodied by a man who accepts all of his emotions, understands the connectedness of humanity, and is devoted to helping others. Join us as Miguel explains how the sacred masculine is increasingly being recognized as a new model of masculinity to replace the old ideas of what it meant to be a man. This new man embraces all of his humanity and recognizes that part of this is the courage to feel, express and honor the full spect...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Ethics & Morality General Inspiration & Hope Interview LifeHelper Men's Issues Podcast Relationships Self-Help Spirituality The Psych Central Show Source Type: blogs
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