Male infertility will be ignored as long as conception is seen as a woman ’s issue | Barbara Ellen
Could prejudice explain why research into sperm counts fails to win funding?Are men ignoring their “biological clocks”? Or is it rather that they are not adequately served by science, which, in turn is being stymied by lack of funding?The Human Fertilisation and Embryology Authority ’s2014-16 report reveals, among other findings, that male infertility is the most common reason (37%) for British couples seeking IVF. Meanwhile, elsewhere, it ’s revealed that male infertility is considered such an “unsexy” research area that it’s nigh-on impossible to get funding. While pooled 2017 research found that sperm counts in the US, Europe, Australia and New Zealand hadhalved in 40 years, and one in 20 young men had a low sperm count, the science of male infertility remains stuck at the 1950s level of counting sperm on laboratory slides.Continue reading...
ConclusionsAge of the mother, outcome of the first pregnancy, and treatment factors affect the length of the interpregnancy interval. Because short IPI has been associated with poor outcomes, women who are at risk for short IPI should be counseled about these outcome risks.
Publication date: Available online 18 July 2018Source: PeptidesAuthor(s): Sevil Arabaci Tamer, Alper Yildirim, M. Kutay köroğlu, Özge Çevik, Feriha Ercan, Berrak Ç. YeğenAbstractTesticular torsion causes ischemia-reperfusion injury and an increased risk of infertility. Nesfatin-1 is a novel peptide with antioxidant, anti-inflammatory and anti-apoptotic properties. In the present study, we aimed to investigate the putative beneficial effects of nesfatin-1 on oxidative injury and impaired testicular function induced by testis torsion. Under anesthesia, male Sprague-Dawley rats (180-230 g; n = ...
Conditions: Infertility, Female; Endometrium Intervention: Procedure: UC-MSCs therapy Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Recruiting
Acephalic spermatozoa syndrome is a severe teratozoospermia that leads to male infertility. Our previous work showed that biallelic SUN5 mutations are responsible for acephalic spermatozoa syndrome in about half of affected individuals, while pathogenic mechanisms in the other individuals remain to be elucidated. Here, we identified a homozygous nonsense mutation in the testis-specific gene PMFBP1 using whole-exome sequencing in a consanguineous family with two infertile brothers with acephalic spermatozoa syndrome.
Authors: Zarandi NP, Galdon G, Kogan S, Atala A, Sadri-Ardekani H Abstract While the survival rate of children with cancer is increasing, preserving fertility for prepubertal boys is still a challenge. Although intracytoplasmic sperm injection (ICSI) using frozen sperms has revolutionized infertility treatment, it is not applicable for the patients who undergo chemotherapy before puberty since spermatogenesis has not begun. Therefore, preserving spermatogonial stem cells (SSCs) as an experimental option can be provided to prepubertal patients at a risk of damage or loss of their SSCs due to cancer treatments and de...
Conditions: Mrk Anomaly; Infertility, Female Intervention: Procedure: uterus transplantation surgery and IVF Sponsors: Sahlgrenska University Hospital, Sweden; Saint Joseph University, at Bellevue Medical Centre Recruiting
Condition: Infertility, Male Interventions: Dietary Supplement: Dietary Supplement with L-carnitine (FertilHom); Dietary Supplement: Control Dietary Supplement Sponsor: NATURAmedicatrix Sàrl Not yet recruiting
CONCLUSION: Despite a more frequent presentation with advanced disease, colorectal cancer has a similar prognosis in pregnancy when compared with the general population. Diagnostic interventions and treatment should not be delayed due to the pregnancy but a balance between maternal and foetal wellbeing must always be kept in mind. PMID: 30010511 [PubMed - as supplied by publisher]