Clinical application of targeted next-generation sequencing on fetuses with congenital heart defects.

CONCLUSIONS: Targeted NGS of fetuses with isolated and non-isolated CHDs achieved a high diagnostic yield in our cohort, with an acceptable turnaround time for the prenatal setting. Our results have important implications for clinical management and genetic counseling.
PMID: 29536580 [PubMed - as supplied by publisher]

Source: The Ultrasound Review of Obstetrics and Gynecology - March 13, 2018 Category: Radiology Authors: Hu P, Qiao F, Wang Y, Meng L, Ji X, Luo C, Xu T, Zhou R, Zhang J, Yu B, Wang L, Wang T, Pan Q, Ma D, Liang D, Xu Z Tags: Ultrasound Obstet Gynecol Source Type: research