Follow-up Creatinine Level Is an Important Predictive Factor of In-hospital Mortality in Cirrhotic Patients with Spontaneous Bacterial Peritonitis.

Follow-up Creatinine Level Is an Important Predictive Factor of In-hospital Mortality in Cirrhotic Patients with Spontaneous Bacterial Peritonitis. J Korean Med Sci. 2018 Mar 19;33(12):e99 Authors: Jun BG, Lee WC, Jang JY, Jeong SW, Kim YD, Cheon GJ, Lee YN, Kim SG, Kim YS, Cho YS, Lee SH, Kim HS Abstract BACKGROUND: Spontaneous bacterial peritonitis (SBP) is one of the severe complications of liver cirrhosis. Early detection of high-risk patients is essential for prognostic improvement. The aim of this study is to investigate the predictive factors related to in-hospital mortality in patients with SBP. METHODS: This was a retrospective study of 233 SBP patients (181 males, 52 females) who were admitted to four tertiary referral hospitals between August 2002 and February 2013. The patients' laboratory and radiologic data were obtained from medical records. The Child-Turcotte-Pugh (CTP) score and model for end-stage liver disease sodium model (MELD-Na) scores were calculated using the laboratory data recorded at the time of the SBP episode. RESULTS: The causes of liver cirrhosis were hepatitis B (44.6%), alcohol (43.8%), hepatitis C (6.0%), and cryptogenic cirrhosis (5.6%). The mean MELD-Na and CTP scores were 27.1 and 10.7, respectively. Thirty-one of the patients (13.3%) died from SBP in hospital. Multivariate analysis revealed that maximum creatinine level during treatment was a statistically significant factor for in-hospital mortality (P = 0.0...
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

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CONCLUSIONS: In this study, we generated a new mouse model of multi-step thyroid cancer dedifferentiation with evidence of progression from PTC to PDTC and ATC. Further, PDTC in these mice showed two distinct histologic appearances correlated with levels of expression of thyroid differentiation and iodine metabolism genes, suggesting a possibility of existence of two PDTC types with different functional characteristics and potential implication for therapeutic approaches to these tumors. PMID: 31298630 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
Authors: An J, Lee JS, Sharpsten L, Wilson AK, Cao F, Tran JN Abstract Objective: To describe pill burden before and after hepatitis C virus (HCV) treatment initiation among patients newly treated for HCV infection, and to evaluate the association between HCV pill burden and gaps in HCV therapy. Methods: This was a retrospective administrative claims study of patients treated with direct-acting antivirals (DAAs) for HCV from 01 November 2013 - 31 July 2016. HCV pill burden was defined as the pill count per day for the index HCV regimen. Mean overall pill burden (HCV medications plus non-HCV medications) was calcula...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Publication date: October 2019Source: Accident Analysis &Prevention, Volume 131Author(s): Anja Valen, Stig Tore Bogstrand, Vigdis Vindenes, Joachim Frost, Magnus Larsson, Anders Holtan, Hallvard GjerdeAbstractFatal road traffic crashes are often related to speeding, non-use of a seatbelt, and alcohol/drug-impaired driving. The aim of this study was to examine associations between driving under the influence of drugs and/or alcohol and driver-related risk factors that have been reported as significantly contributing causes of fatal road traffic crashes. The data were extracted from Norwegian road traffic crash registrie...
Source: Accident Analysis and Prevention - Category: Accident Prevention Source Type: research
Publication date: Available online 13 July 2019Source: Materials Chemistry and PhysicsAuthor(s): Linlin Fan, Dongbin Xiong, Xifei LiAbstractSnO2/graphene aerogels (SnO2/GAs) nanocomposites are fabricated via a cost-efficient hydrothermal and large-scalable strategy. In present study, SnO2 nanoparticles possessing various contents are loaded onto the surface of GAs to optimize the electrochemical activity of nanocomposite systems as anodes for lithium ion batteries (LIBs) and sodium ion batteries (SIBs). SEM and TEM characterizations obviously show SnO2 nanoparticles with the diameter of 5–8 nm are dispersed homogen...
Source: Materials Chemistry and Physics - Category: Materials Science Source Type: research
Publication date: November 2019Source: Carbon, Volume 153Author(s): Beibei Yang, Sitong Liu, Huaihe Song, Jisheng ZhouAbstractThe design of carbon anode materials with both high gravimetric and volumetric performances is one of the main limitations in the real applications of sodium-ion batteries (SIBs). Herein, we develop novel micro/nanostructure carbon microspheres (CMSs) assembled of onion-like carbons via an in situ pyrolysis approach. When used as anode materials for SIBs, the CMSs electrode possesses a high pressing density of 1.36 g cm−3. The CMSs exhibit a high reversible gravimetric capacity of 275 mAh ...
Source: Carbon - Category: Materials Science Source Type: research
Publication date: November 2019Source: Carbon, Volume 153Author(s): Kunlin Liu, Xuewen Zheng, Keke Wang, Chengyang Wang, Mingming ChenAbstractNitrogen-doping can increase the charge density and the wettability of electrode materials, to further reinforce the electrochemical performances of energy storage devices. It is difficult to directly convert small molecular nitrogen-containing organics into N-doped porous carbon materials. Here we demonstrate a bottom-up strategy to prepare N-doped porous carbons by sodium metal-assisted carbonization of pyrrole. Pyrrole is not only a nitrogen source, but also a carbon source. In th...
Source: Carbon - Category: Materials Science Source Type: research
CONCLUSIONS: Suicidal risks were high in mood disorders: ideation was highest with BD type II, attempts and suicides (especially violent) with BD type I. Several risk factors for suicidal acts differed between BD versus MDD patients.Declaration of interestNo author or immediate family member has financial relationships with commercial entities that might appear to represent potential conflicts of interest with the information presented. PMID: 31292010 [PubMed - as supplied by publisher]
Source: The British Journal of Psychiatry for Mental Science - Category: Psychiatry Tags: Br J Psychiatry Source Type: research
ConclusionNAFLD patients had lower mortality and complication rates following BS. A significant postsurgical weight loss should attenuate liver inflammation and fibrosis, and therefore has the potential to stop or even reverse progression of liver disease.
Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
Publication date: Available online 12 July 2019Source: LWTAuthor(s): Siridevi G. B, Devendra Havare, Basavaraj K, Pushpa S. MurthyAbstract:Arabica coffee is fermented to obtain intense flavor profile and finds elusive prospects in the coffee industry. The Arabica coffee mucilage constitute 2–5% of the fruit dry weight with 94% moisture, 4% sugar, 0.7% protein and 1–3% pectin. Inductive isolation and screening of functional attributes of microbial strains were examined. Fermentative vigor along with the enzymatic progression of the microbes was streamlined and the potential isolates of consortia were optimized. ...
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
Publication date: Available online 21 December 2018Source: Journal of Advanced ResearchAuthor(s): Undurti N. DasAbstractIt has been suggested that hepatitis B virus (HBV)- and hepatitis C virus (HCV)-induced hepatic damage and cirrhosis and associated hypoalbuminemia, non-alcoholic fatty liver disease (NAFLD), and alcoholic fatty liver disease (AFLD) are due to an imbalance between pro-inflammatory and anti-inflammatory bioactive lipids. Increased tumour necrosis factor (TNF)-α production induced by HBV and HCV leads to a polyunsaturated fatty acid (PUFA) deficiency and hypoalbuminemia. Albumin mobilizes PUFAs from t...
Source: Journal of Advanced Research - Category: Research Source Type: research
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