Lung Transplantation for Scleroderma Lung Disease: An International Multicenter Observational Cohort Study

Due to its multisystemic nature, scleroderma is considered a relative contra-indication to lung transplantation in many centers. However, recent studies suggest similar post-transplant outcomes in patients with scleroderma compared to those with other causes of interstitial lung disease (ILD). Furthermore, whether scleroderma-associated pulmonary arterial hypertension (PAH) influences post-transplant outcomes remains unknown. Our objective here was to assess the indications, survival, and prognostic factors of lung or heart-lung transplantation for scleroderma lung disease.

Source: The Journal of Heart and Lung Transplantation - March 15, 2018 Category: Transplant Surgery Authors: Pauline Prad ère, Igor Tudorache, Jesper Magnusson, Laurent Savale, Olivier Brugiere, Benoît Douvry, Martine Reynaud-Gaubert, Johanna Claustre, Aurélie Le Borgne, Are M. Holm, Hans Henrik Schultz, Christiane Knoop, Laurent Godinas, Andrew J. Fisher, Sa Source Type: research