Inter-institutional analysis demonstrates the importance of lower than previously anticipated dose regions to prevent late rectal bleeding following prostate radiotherapy.

CONCLUSION: We have demonstrated the importance of integrating datasets from multiple institutions, thereby reducing the impact of intra-institutional dose-volume parameters explicitly correlated with prescription dose levels. This uncovered an unexpected emphasis on sparing of the low to intermediate rectal dose range in the etiology of late rectal bleeding following prostate radiotherapy. PMID: 29530433 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29530433?dopt=Abstract

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 9, 2018 Category: Radiology Authors: Thor M, Jackson A, Zelefsky MJ, Steineck G, Karlsdòttir A, Høyer M, Liu M, Nasser NJ, Petersen SE, Moiseenko V, Deasy JO Tags: Radiother Oncol Source Type: research