NKDEP Working Group urges better electronic health record-keeping to improve chronic kidney disease outcomes

NKDEP working group sets goals to improve electronic health records and standardize their use, helping improve care for people with chronic kidney diseases.
Source: NIDDK News - Category: Endocrinology Source Type: news

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CONCLUSIONS: Metabolic reprogramming promoted renal interstitial fibrosis, which leads to alteration of cell energy metabolism model. PMID: 30024614 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Authors: Meng H, Lockshin C, Jain S, Shaligram U, Martinez J, Genkin D, Hill DB, Ehre C, Clark D, Hoppe H Abstract While protein therapeutics are invaluable in managing numerous diseases, many require frequent injections to maintain therapeutically effective concentrations, due to their short half-life in circulation. PolyXen™, a platform technology employing biodegradable, non-immunogenic and hydrophilic polysialic acids (PSA) for drug delivery, is being utilized to overcome such limitations, thereby enabling the clinical utility of a broad range of protein therapeutics. Here, we report the recent progress o...
Source: Recent Patents on Drug Delivery and Formulation - Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research
Publication date: Available online 19 July 2018Source: Canadian Journal of CardiologyAuthor(s): Lorenzo Azzalini, Soledad Ojeda, Ozan M. Demir, Joseph Dens, Masaki Tanabe, Alessio La Manna, Susanna Benincasa, Barbara Bellini, Enrico Poletti, Davide Maccagni, Francisco Hidalgo, Jorge Chavarría, Joren Maeremans, Giacomo Gravina, Eligio Miccichè, Guido D’Agosta, Giuseppe Venuti, Corrado Tamburino, Manuel Pan, Mauro CarlinoAbstractBackgroundChronic total occlusion (CTO) percutaneous coronary intervention (PCI) is associated with high contrast volumes, which can be particularly deleterious in chronic kidney ...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Urea and creatinine in saliva have been reported to be possible markers of chronic kidney disease (CKD) in humans. The aim of this study was to assess if urea and creatinine could be measured in canine saliva,...
Source: BMC Veterinary Research - Category: Veterinary Research Authors: Tags: Research article Source Type: research
AbstractPurposeThe complexity of chronic kidney disease –mineral and bone disorder (CKD–MBD) led to many preclinical and clinical trials. The role of sclerostin in renal pathophysiology remained unresolved, and question whether sclerostin is related to cardiovascular (CV) outcome in patients with CKD is still open. Our aim was to evaluate the possibl e association between serum sclerostin levels and carotid intima-media thickness (CIMT) in CV pathophysiology through various CKD stages.MethodsEighty-eight patients in various CKD stages were involved in this analysis. CKD-EPI (Chronic kidney disease Epidemiology ...
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research
AbstractPurpose of ReviewThe choice of optimum transplant in a patient with type 1 diabetes mellitus (T1DM) and chronic kidney disease stage V (CKD V) is not clear. The purpose of this review was to investigate this in more detail —in particular the choice between a simultaneous pancreas-kidney transplantation (SPKT) and living donor kidney transplantation (LDKT), including recent evidence, to aid clinicians and their patients in making an informed choice in their care.Recent FindingsAnalyses of large databases have recently shown SPKT to have better survival rates than a LDKT in the long-term, despite an early incre...
Source: Current Diabetes Reports - Category: Endocrinology Source Type: research
In conclusion, ART exhibited protective effect on HG-induced HBZY-1 cells by inhibiting the inflammatory response, oxidative stress and ECM accumulation. The TLR4/NF-κB/NLRP3 inflammasome pathway was involved in the protective effect of ART. The results suggested that ART might be a potential therapy agent for the DN treatment.
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
ConclusionseGFR markers appear to have relatively low short-term within-person variability, whereas variability in albuminuria appears to be high, making it difficult to distinguish random variability from meaningful biologic changes.
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Abstract It is believed that the vasopressinergic system plays an important role in the pathogenesis of chronic kidney disease (CKD). The aim of this study was to evaluate the effect of CKD on changes in vasopressin system expression in the kidney cortex in rats with nephrectomy. The study was performed on 4 groups of Sprague Dawley (SPRD) rats: a control group (CN), 1/2 nephrectomy (N1/2), 2/3 nephrectomy (N2/3), and 5/6 nephrectomy (N5/6). Blood and the kidney cortex were collected to evaluate plasma copeptin concentrations and mRNA expressions of V1a vasopressin receptors (V1aR) and V2 vasopressin receptors (V2...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
This study investigated whether older adults with chronic kidney disease are at increased risk of falling and serious injury from falls. What factors might contribute to higher risk?Preventing Chronic Disease
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news
More News: Chronic Kidney Disease | Electronic Health Records (EHR) | Urology & Nephrology