Use of Aromatase Inhibitors in IVF for Fertility Preservation of Non-Breast Cancer Patients: A Case Series.
CONCLUSIONS: COH with aromatase inhibitors is apparently effective in non-breast cancer patients and spares exposure to high E2 levels. PMID: 29527850 [PubMed - in process]
The Pan-Mass Challenge fundraiser has raised a record-breaking $63 million for Dana-Farber Cancer Institute, the largest financial gift in the cancer hospital ’s history. The PMC, which hosts a two-day, 192-mile bike ride to raise funding for Dana-Farber and The Jimmy Fund, has raised more than $717 million for the health system since 1980, helping to support development of 41 of 100 new FDA-approved cancer drugs. “I am extremely grateful for th e generous support received from the Pan-Mass…
Publication date: Available online 18 October 2019Source: Molecular Aspects of MedicineAuthor(s): Lukas Valihrach, Peter Androvic, Mikael KubistaAbstractSuccessful treatment of cancer depends on early diagnosis and effective monitoring of patients’ response to therapy. Traditional tools based on tumor biopsies lack the sensitivity and specificity to capture cancer development in its early phases and are not applicable for continuous monitoring. To overcome these barriers, liquid biopsies have been introduced as a minimally invasive and cost-efficient means of diagnosis with high level of specificity and sensitivity. ...
CONCLUSIONS: The CTTA models based on contrast-enhanced CT images had a high value in differentiating fpAML from chRCC. PMID: 31625454 [PubMed - in process]
Contributors : Y Li ; F Huang ; S ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGlucose metabolism makes contributions to the development of pancreatic ductal adenocarcinoma (PDAC). Meanwhile, circular RNAs, a subset of noncoding RNAs, plays an important role in glucose metabolism and cancer progression. Analysis of low-glucose-treated and normal-glucose-treated MIA PaCa-2 cells from 6 samples (3 samples each group) was conducted. Results indicate insight into molecular signature of the pathogenesis of PDAC in abberant glucose metabolism.
CONCLUSION: Radiolabelled PSMA imaging seems to be useful in analyzing glioma/glioblastoma. Further studies enrolling a wider population are needed to clarify the real clinical and diagnostic role of radiolabelled PSMA in this setting and its possible position in the diagnostic flow-chart. PMID: 31625482 [PubMed - as supplied by publisher]
ConclusionsIn the appropriately selected patient, OSS in upper tract, bladder and urethral carcinoma has comparable oncological outcomes to radical surgery and with the additional benefit of improved quality of life.
Publication date: Available online 18 October 2019Source: Evaluation and Program PlanningAuthor(s): Rachel Claire Mitchell, Glenn D. Israel, David C. Diehl, Sebastian Galindo-GonzalezAbstractThe Southeastern Coastal Center for Agricultural Health and Safety (SCCAHS) is one of many newly-funded federal research centers, housing five multidisciplinary research projects and seven pilot projects, and serving a multi-state region. In the early stages of such a complex project, with multiple teams separated by geography and disciplines, the evaluation program has been integral in connecting internal and external stakeholders at ...
ConclusionGCT primary of the liver must be considered in the differential diagnosis of liver tumors.
ConclusionMRI has good diagnostic performance for assessing myometrial invasion in patients with endometrial cancer, especially in patients younger than 60 years old. Dynamic contrast-enhanced MRI and diffusion weighted imaging can help improve sensitivity and specificity for detecting myometrial invasion. MRI shows high specificity for detecting cervical invasion and lymph node metastases in endometrial cancer.
Authors: Philipp-Dormston WG, Battistella M, Boussemart L, Di Stefani A, Broganelli P, Thoms KM Abstract Introduction: Actinic keratosis (AK) is a chronic skin condition that can be a precursor to cutaneous squamous cell carcinoma. AK can recur and patients are likely to undergo multiple treatments. It is important that AK lesions are managed appropriately, and that patients are involved in treatment decisions. Materials and methods: The Supporting Professional Expertise in AK (SPEAK) program aims to facilitate this patient-centered care by identifying patient needs and aiding healthcare practitioners (HCPs) in sel...
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