Early Improvement in Pain and Functional Outcome but Not Quality of Life After Surgery for Metastatic Long Bone Disease.

CONCLUSIONS: Surgical management of metastatic long bone disease substantially improves patients' functional outcome and pain as early as 2 weeks postoperatively and should be considered for impending or pathologic fracture in patients whose survival is expected to be longer than 2 weeks provided that there are no immediate contraindications. Quality of life in this patient population did not improve, which may be a function of patient selection, concomitant chemoradiotherapy regimens, disease progression, or terminal illness, and this merits further investigation.
LEVEL OF EVIDENCE: Level II, therapeutic study.
PMID: 29529637 [PubMed - in process]

Source: Clinical Orthopaedics and Related Research - March 1, 2018 Category: Orthopaedics Authors: Nooh A, Goulding K, Isler MH, Mottard S, Arteau A, Dion N, Turcotte R Tags: Clin Orthop Relat Res Source Type: research